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February 17, 2010
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Forget venture capital. Forget selling the firm outright. ImmuneWorks, an Indianapolis-based biotech firm, is taking a different route to get early-stage funding for money-sucking biotech drug development. The company signed a joint development agreement with Lung Rx, a subsidiary of Maryland-based United Therapeutics Corp. Lung Rx will fund ImmuneWorks' research and development operations with the option of acquiring the firm. ImmuneWorks, based on the research of Dr. David Wilkes at the Indiana University School of Medicine, is trying to develop treatments for orphan lung diseases, which affect fewer than 200,000 people nationwide.

Looks like the changing of the guard in Indianapolis-based Eli Lilly and Co.’s research operations is going beyond Dr. Steve Paul. In the same month Paul retired, his top lieutenant, Dr. William Chin, has taken a newly created job at Harvard Medical School. Chin was Lilly’s senior vice president for discovery research and clinical investigation. Paul was replaced by Jan M. Lundberg, former head of global discovery research at London-based AstraZeneca plc. Looks like Lundberg will be bringing in his own team.

Indiana University School of Medicine researchers have identified a mechanism by which tuberculosis evades the body’s immune system and have identified a compound that blocks the tuberculosis bacteria’s ability to survive. Those insights could lead to new drugs to treat tuberculosis. Zhong-Yin Zhang, a professor of biochemistry and molecular biology, was the lead author explaining the discoveries in in this week’s online early edition of the Proceedings of the National Academy of Sciences. Zhang’s team also described an anti-tuberculosis compound they have synthesized, A09. The compound is now being evaluated in animals at Johns Hopkins University School of Public Health.


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  1. How much you wanna bet, that 70% of the jobs created there (after construction) are minimum wage? And Harvey is correct, the vast majority of residents in this project will drive to their jobs, and to think otherwise, is like Harvey says, a pipe dream. Someone working at a restaurant or retail store will not be able to afford living there. What ever happened to people who wanted to build buildings, paying for it themselves? Not a fan of these tax deals.

  2. Uh, no GeorgeP. The project is supposed to bring on 1,000 jobs and those people along with the people that will be living in the new residential will be driving to their jobs. The walkable stuff is a pipe dream. Besides, walkable is defined as having all daily necessities within 1/2 mile. That's not the case here. Never will be.

  3. Brad is on to something there. The merger of the Formula E and IndyCar Series would give IndyCar access to International markets and Formula E access the Indianapolis 500, not to mention some other events in the USA. Maybe after 2016 but before the new Dallara is rolled out for 2018. This give IndyCar two more seasons to run the DW12 and Formula E to get charged up, pun intended. Then shock the racing world, pun intended, but making the 101st Indianapolis 500 a stellar, groundbreaking event: The first all-electric Indy 500, and use that platform to promote the future of the sport.

  4. No, HarveyF, the exact opposite. Greater density and closeness to retail and everyday necessities reduces traffic. When one has to drive miles for necessities, all those cars are on the roads for many miles. When reasonable density is built, low rise in this case, in the middle of a thriving retail area, one has to drive far less, actually reducing the number of cars on the road.

  5. The Indy Star announced today the appointment of a new Beverage Reporter! So instead of insightful reports on Indy pro sports and Indiana college teams, you now get to read stories about the 432nd new brewery open or some obscure Hoosier winery winning a county fair blue ribbon. Yep, that's the coverage we Star readers crave. Not.