Medical Research

Q&A

December 8, 2010
J.K. Wall
Molecular biologist,David G. Skalnik will become associate dean for research and graduate education at the IUPUI School of Science in January. Since 1991, Skalnick has been a researcher at the Indiana University School of Medicine, leading a team of three in the study of epigenetics—factors that influence whether certain genes are turned on or turned off.
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Lilly, Acrux receive FDA approval for Axiron

November 24, 2010
 IBJ Staff and Bloomberg News
The companies believe the underarm testosterone solution has the potential to realize sales of more than $1 billion a year in the United States.
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Study: Arthritis drug co-developed by Lilly shows promise

November 12, 2010
 IBJ Staff and Bloomberg News
Lilly paid $90 million in 2009 to acquire the global rights to the treatment in a bid to beef up its pipeline of medications for autoimmune diseases.
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Lilly makes $300M deal for Philadelphia drug company

November 8, 2010
J.K. Wall
Eli Lilly said it will acquire Avid Radiopharmaceuticals, maker of an experimental agent that could help identify patients with Alzheimer's disease. The price could climb to $800 million if the agent is commercially successful.
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UPDATE: Lilly, others see stock slide after drug rejection

October 20, 2010
Bloomberg News
Stock in Eli Lilly and Co., Amylin Pharmaceuticals Inc. and Alkermes Inc. dropped after they were rebuffed a second time in a bid to gain U.S. approval of a once-weekly version of the diabetes drug Byetta.
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IU shrink explores mental health blood tests

October 13, 2010
J.K. Wall
Dr. Alexander B. Niculescu, a psychiatrist at the IU School of Medicine, has won a five-year, $1.5 million grant from the National Institutes of Health to hunt for the presence of certain proteins in the blood that would indicate that a patient suffers from a mood disorder, which afflicts one in five Americans.
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Cook stent could prevent more amputations, study finds

September 27, 2010
Bloomberg News
A drug-coated stent from Indiana-based Cook Medical was more effective than standard therapy for patients with blockages in an upper-leg artery, a study found.
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After health reform, Lilly looking for more

September 1, 2010
J.K. Wall
The health reform debate may have ended in Congress, but Eli Lilly and Co. remains active, sponsoring a talk about the positives of the bill—and calling for further government efforts to help pharmaceutical research and development.
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Pearl IRB first firm in state to pre-screen clinical drug trialsRestricted Content

August 21, 2010
Chris O'Malley
Two former Eli Lilly and Co. employees launched the firm that promises to attract more clinical trial business to the state.
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Cancer drug developer Endocyte files for IPO

August 18, 2010
Scott Olson
The company, headquartered at Purdue Research Park, said the number of shares to be offered and their price range have yet to be determined.
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Lilly Alzheimer's drug prospect only the latest to fail

August 18, 2010
Bloomberg News
A dozen potential products designed to slow or stop clumps of protein from forming in the brain, a condition linked to the disease since 1906, have failed in mid- to late-stage testing since 2003.
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Lilly halts development of Alzheimer's drug

August 17, 2010
 IBJ Staff and Associated Press
Studies showed that the treatment did not slow the disease's progression. It's just the latest setback for the pharmaceutical giant, which lost a patent lawsuit over a major drug last week and faces an unprecedented number of patent expirations through 2014.
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Indiana universities offer cash incentives for technology transfer

August 7, 2010
 IBJ Staff
The Indiana Clinical and Translational Sciences Institute awarded $750,000 to 10 teams of researchers.
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Lilly's Alzheimer's gamble takes aim at $10 billion in patent losses

July 13, 2010
Bloomberg News
Both of Lilly's late-stage treatments are designed to reduce plaque in the brain called beta amyloid, thought by researchers to be a main contributor to Alzheimer's. A drug that stops or reduces memory loss caused by Alzheimer's may be worth more than $5 billion a year, an analyst says, helping Lilly overcome the coming patent losses on several important pharmaceuticals.
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Q&A

June 23, 2010
J.K. Wall
David Stocum is the director of the Center for Regenerative Biology and Medicine at the IUPUI School of Science. He and his team are studying how amphibians regenerate parts of their bodies to see if there are ways to induce humans to regenerate tissue that is lost or damaged. The center has about 20 researchers and funding of about $14 million to fuel its quest.
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Genetic testing could spur Erbitux drug sales

June 1, 2010
Bloomberg News
The drugmakers are counting on screening for the so-called K-ras gene to spur use of Erbitux in metastatic colorectal cancer.
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Cancer researcher battling Semafore in courtRestricted Content

May 29, 2010
Chris O'Malley
Former collaborator alleges firm breached its agreement with him and refused to pay royalty income.
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Indiana's growth in life sciences jobs beats national average

May 8, 2010
 IBJ Staff
Bloomington led the nation as the No. 1 small city in medical devices and equipment.
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Closing of Purdue's Chao Center is setback for BioCrossroads

May 1, 2010
J.K. Wall
The university is hoping to find a private company to take over the 5-year-old facility, which formulated and manufactured small batches of drugs used in clinical trials.
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WellPoint gets lashing from Sebelius, again

April 26, 2010
J.K. Wall
Indianapolis-based health insurer trades jabs with U.S. health secretary after Reuters story claims insurer deliberately cancels coverage for breast cancer patients.
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Medical device startup FlowCo enlists Guidant alums

April 24, 2010
Chris O'Malley
The upstart developer of a device to help doctors choose the right-sized stent to prop open clog-prone arteries has brought aboard former Guidant Corp. executives, including Bill McConnell. Their regulatory and marketing expertise could help FlowCo Inc. bring its artery-measurement product to market as soon as 2011.
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Harlan Labs names new CEO

April 23, 2010
 IBJ Staff
The Indianapolis-based provider of clinical research animals has promoted senior manager Hans Thunem to its top spot.
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Roche taps new local CEO

January 12, 2010
J.K. Wall
Roche Diagnostics named a new CEO for its North American operations Tuesday to replace Michael Tillmann, who resigned on Friday.
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$60M Lilly Endowment grant to fund IU physician research

December 15, 2009
Peter Schnitzler
Indiana University, which has received nearly $600 million from the endowment over the last three decades, will leverage the new gift to increase its scientific discoveries and commercialize life science innovations.
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Company's medical device earns expedited review

December 9, 2009
FAST Diagnostics LLC said initial human trials on its method to measure kidney function faster and more accurately than existing techniques could begin as early as next year, with commercialization following by 2012.
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