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Eli Lilly neuroscience chief resigns

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Eli Lilly and Co. is losing its head of neuroscience research, the company confirmed.

David Bredt, vice president of neuroscience research, has resigned effective Friday “to pursue other opportunities,” according to Lilly spokeswoman Judy Kay Moore. Bredt had overseen Lilly’s development of various drugs, including molecules in late-stage human testing to treat Alzheimer’s disease and depression.

In addition to those Phase 3 drug candidates, Lilly has three neuroscience drugs in Phase 2 clinical testing. They include a schizophrenia drug like Lilly’s blockbuster Zyprexa that does not appear to cause the side effects that Zyprexa does, as well as a drug to treat alcohol dependency and another to treat agitation in Alzheimer’s patients.

But Bredt also oversaw the major failure of a second experimental Alzheimer’s drug. Lilly halted a Phase clinical trial of semagacestat in August after it worsened the condition of patients.

“We at Lilly thank Dr. Bredt for his many significant contributions to our neuroscience portfolio over the past several years and, before that, as vice president of integrative biology. We wish him well in his future endeavors,” wrote Moore in an e-mail.

She added, “Lilly has a strong history in neuroscience research and development, and neuroscience remains a major therapeutic focus of ours.” She said Lilly would begin a search for a successor.

Bredt came to Lilly in 2004 after many years at the the University of California at San Francisco Medical School. He did his graduate work at Johns Hopkins University in Baltimore, conducting research that greatly advanced insights on nitric oxide as a neurotransmitter in the brain, according to a 2005 article in a Johns Hopkins newsletter.

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  • News to Make you Shake your Head
    http://politifi.com/news/Pennsylvania-Judge-Found-Guilty-in-Kids-for-Cash-Scandal-1659556.html

    And this case as I understand the Judge was working with drug companies to Hold so called Troubled Kids to experiment with Mood drugs. One person was to have Killed them selves over the Matter!

    Any links!?
  • History Tell us What is!
    I was just thinking so was this person. Linked up with Obama Care! And the cover for the drug companies and all the Unconstitutional Tort Claim reform! So was he behind The push of the Human Micro Chip Implants for the Wirless Medical records system so wanted? Was he behind the cover for the Drug Companies that have been seeking to make drugs to cover the EMF plague because of the control of the wirless grid? That the FCC is to be over! Reminder World War Two Was in part fought to control the Air waves! It just so happens to be the the drug in question is one that is to cover for such II-ffects! For those that reject the Historical facts of the past will carry out them gain! This was known long ago with the testing done to create Cell phones for the Open market!

    Note The Movie Valkyrie was based on such historical fact! And the Use of Amalgam.

    Here is some case History
    As of 2002!
    http://www.philipcoppens.com/woodpecker.html

    I sight such History as I research History for my book Elisheva & the Way Stones. on www.writing.com

    With "Amalgam" Letâ??s Not forget the Use of psychotronics or spelled with "M"

    Psychotromics and the cold War and the Lsd Trials and the Wood pecker. And part of what was the S.S. of Hitler!

    The key provision in Senators Lindsey Graham Chuck Schumer amnesty bill backed by President Obama is a new mandated Federal Biometric ID card or The S Chip or Micro Chip Human Implant that Radio Frequency Identification chips (RFID) would be required for any person to hold a job in the United States legally.


    This card would include untold amounts of personal information (like gun ownership) and biometric tracking technology that would allow government bureaucrats to track our every move. Was not the History behind "Amalgam" and the S.S. enough? Many Union Drugs are used to cover the Effects of the EMF Plague, Tinnitus isn't a disease, and itâ??s not schizophrenia


    As they also seek to use this S chip Human microchip implants, the last time this kind of crap was left to run amuck World War two took place 2 nukes was dropped 15 kilotons each was drop and Millions died to stop it all then the trails of Nuremberg Germany came and went this is not funny not funny at all.

    Note the Last Living person of The Nukes Dropped on Japan have passed away this Year 2010 God Rest their Souls


  • Bad drugs
    Oh yes The War On Drugs is A backed Lie, the only Drug War for lack of Better terms is in the White house and Stock Market and Congresses Fight of Tax and Control to compete with drug Companies production of Drugs that are made to do the same thing the Natural ones do,I so as to point out As like the Simple Over demonism of Marijuana, Marijuana has far less side Affects if any for the drug Trial Lawyers to fight over.

    I mean come on Seroquel law suits $520 million in pay outs


    Bernstein Liebhard LLP
    10 East 40th Street, 22nd Floor
    New York, New York 10016
    Toll Free: (877) 779-1414
    Telephone: (212) 779-1414
    Fax: (212) 779-3218
    www.bernlieb.com http://www.bernlieb.com/



    Bruce Michael Anderson
    www.writing.com
  • This does not match up
    They include a schizophrenia drug like Lillys blockbuster Zyprexa that does not appear to cause the side effects that Zyprexa does, as well as a drug to treat alcohol dependency and another to treat agitation in Alzheimers patients!

    With All do respect! How Can the same drug "not" have Bad reactions?

    Bruce Michael Anderson
    www.writing.com

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  1. PJ - Mall operators like Simon, and most developers/ land owners, establish individual legal entities for each property to avoid having a problem location sink the ship, or simply structure the note to exclude anything but the property acting as collateral. Usually both. The big banks that lend are big boys that know the risks and aren't mad at Simon for forking over the deed and walking away.

  2. Do any of the East side residence think that Macy, JC Penny's and the other national tenants would have letft the mall if they were making money?? I have read several post about how Simon neglected the property but it sounds like the Eastsiders stopped shopping at the mall even when it was full with all of the national retailers that you want to come back to the mall. I used to work at the Dick's at Washington Square and I know for a fact it's the worst performing Dick's in the Indianapolis market. You better start shopping there before it closes also.

  3. How can any company that has the cash and other assets be allowed to simply foreclose and not pay the debt? Simon, pay the debt and sell the property yourself. Don't just stiff the bank with the loan and require them to find a buyer.

  4. If you only knew....

  5. The proposal is structured in such a way that a private company (who has competitors in the marketplace) has struck a deal to get "financing" through utility ratepayers via IPL. Competitors to BlueIndy are at disadvantage now. The story isn't "how green can we be" but how creative "financing" through captive ratepayers benefits a company whose proposal should sink or float in the competitive marketplace without customer funding. If it was a great idea there would be financing available. IBJ needs to be doing a story on the utility ratemaking piece of this (which is pretty complicated) but instead it suggests that folks are whining about paying for being green.

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