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EU reviews cancer drug from Endocyte, Merck

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Merck & Co. and Endocyte Inc. said Tuesday that European Union regulators will review their drug vintafolide as a treatment for ovarian cancer.

The companies said the European Medicines Agency will review vintafolide as a treatment for ovarian cancer that is resistant to platinum-based chemotherapy. The agency will also review their application for a diagnostic agent that is intended to help identify patients who could benefit from the drug.

Vintafolide is designed to target a folate receptor that appears on cancer cells but doesn't exist on most other cells. Endocyte, based in West Lafayette, said the receptor is found on 80 percent to 90 percent of ovarian and lung cancers.

Vintafolide and the diagnostic agent both have orphan drug status, which means competing products will be barred from the market for up to 10 years if they are approved.

Whitehouse Station, N.J.-based Merck will pay Endocyte $5 million because the application was accepted.

Merck stock fell 9 cents, to $44.10 per share, and Endocyte shares lost 15 cents, to $8.99, in midday trading Tuesday.

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  1. Those of you yelling to deport them all should at least understand that the law allows minors (if not from a bordering country) to argue for asylum. If you don't like the law, you can petition Congress to change it. But you can't blindly scream that they all need to be deported now, unless you want your government to just decide which laws to follow and which to ignore.

  2. 52,000 children in a country with a population of nearly 300 million is decimal dust or a nano-amount of people that can be easily absorbed. In addition, the flow of children from central American countries is decreasing. BL - the country can easily absorb these children while at the same time trying to discourage more children from coming. There is tension between economic concerns and the values of Judeo-Christian believers. But, I cannot see how the economic argument can stand up against the values of the believers, which most people in this country espouse (but perhaps don't practice). The Governor, who is an alleged religious man and a family man, seems to favor the economic argument; I do not see how his position is tenable under the circumstances. Yes, this is a complicated situation made worse by politics but....these are helpless children without parents and many want to simply "ship" them back to who knows where. Where are our Hoosier hearts? I thought the term Hoosier was synonymous with hospitable.

  3. Illegal aliens. Not undocumented workers (too young anyway). I note that this article never uses the word illegal and calls them immigrants. Being married to a naturalized citizen, these people are criminals and need to be deported as soon as humanly possible. The border needs to be closed NOW.

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