IBJNews

Roche acquires Marcadia Biotech

Back to TopCommentsE-mailPrintBookmark and Share

Marcadia Biotech Inc., a Carmel-based biopharmaceutical company founded by former Eli Lilly and Co. executives in 2006, has been acquired by Swiss life sciences giant Roche.

The deal closed Wednesday, confirmed Roche spokesman Geoff Teeter.

“Details of the transaction are not being disclosed at this stage," Roche said in a written statement to IBJ. "Roche will disclose more information on this transaction on publication of our full-year financial report in February.”

Roche’s holdings include Roche Diagnostics in Indianapolis, which has about 3,500 local employees.

Marcadia has about a dozen employees at its 11711 N. Meridian St. headquarters. While relatively small, the firm has raised millions in venture capital.

Marcadia’s chief scientific officer is Richard DiMarchi, who previously headed the biotechnology group at Lilly Research Labs, the research and development arm at Eli Lilly. He is also a professor and researcher at Indiana University, which has rights to some of Marcadia’s experimental drugs.

DiMarchi helped found the company with Gus Watanabe, the former head of Lilly's research laboratories and BioCrossroads chairman, who died in 2009.

Marcadia has been focusing on drugs to treat  metabolic diseases such as diabetes and obesity.

It previously partnered with drug giant Merck & Co. Inc. and with Indianapolis-based Lilly. Last June, Marcadia and Lilly struck a deal to develop short-acting glucagon drugs to treat severe hypoglycemia.

The Carmel company in 2007 raised $15 million in venture capital from Menlo Park, Calif.-based 5AM Investors, Seattle-based Frazier Healthcare Ventures and from locally based Twilight Venture Partners.

Former Twilight partner Kent Hawryluk serves as vice president of business development at Marcadia.

Marcadia’s profile has been rising, with a big external validation coming last year when results of its research on obesity-fighting compounds were published in the scientific journal Nature Chemical Biology, better known as Nature.

Marcadia’s researchers injected into mice a molecule they developed for treating obesity. The molecule decreased body weight by 25 percent and fat mass by 42 percent after one week.

“The results that we saw in these animal models were unprecedented,” Marcadia CEO Fritz French told IBJ at the time.

The promise underscored the need for hundreds of millions of dollars to proceed with human trials and eventually to bring the drug to market.

Neither French nor DiMarchi could be reached for comment Thursday.

Roche is a well-established leader in diabetes research and blood glucose monitoring devices.  Last February, the company announced progress in studies of its weekly taspoglutide drug in reducing blood glucose for those with Type 2 diabetes.

ADVERTISEMENT

Post a comment to this story

COMMENTS POLICY
We reserve the right to remove any post that we feel is obscene, profane, vulgar, racist, sexually explicit, abusive, or hateful.
 
You are legally responsible for what you post and your anonymity is not guaranteed.
 
Posts that insult, defame, threaten, harass or abuse other readers or people mentioned in IBJ editorial content are also subject to removal. Please respect the privacy of individuals and refrain from posting personal information.
 
No solicitations, spamming or advertisements are allowed. Readers may post links to other informational websites that are relevant to the topic at hand, but please do not link to objectionable material.
 
We may remove messages that are unrelated to the topic, encourage illegal activity, use all capital letters or are unreadable.
 

Messages that are flagged by readers as objectionable will be reviewed and may or may not be removed. Please do not flag a post simply because you disagree with it.

Sponsored by
ADVERTISEMENT

facebook - twitter on Facebook & Twitter

Follow on TwitterFollow IBJ on Facebook:
Follow on TwitterFollow IBJ's Tweets on these topics:
 
Subscribe to IBJ
  1. Liberals do not understand that marriage is not about a law or a right ... it is a rite of religous faith. Liberals want "legal" recognition of their homosexual relationship ... which is OK by me ... but it will never be classified as a marriage because marriage is a relationship between a man and a woman. You can gain / obtain legal recognition / status ... but most people will not acknowledge that 2 people of the same sex are married. It's not really possible as long as marriage is defined as one man and one woman.

  2. That second phrase, "...nor make or enforce any law which shall abridge the privileges or immunitites of citizens..." is the one. If you can't understand that you lack a fundamental understanding of the Constitution and I can't help you. You're blind with prejudice.

  3. Why do you conservatives always go to the marrying father/daughter, man/animal thing? And why should I keep my sexuality to myself? I see straights kissy facing in public all the time.

  4. I just read the XIV Amendment ... I read where no State shall deprive any person of life, liberty, or property ... nor make or enforce any law which shall abridge the privileges or immunitites of citizens ... I didn't see anything in it regarding the re-definition of marriage.

  5. I worked for Community Health Network and the reason that senior leadership left is because they were not in agreement with the way the hospital was being ran, how employees were being treated, and most of all how the focus on patient care was nothing more than a poster to stand behind. Hiring these analyst to come out and tell people who have done the job for years that it is all being done wrong now...hint, hint, get rid of employees by calling it "restructuring" is a cheap and easy way out of taking ownership. Indiana is an "at-will" state, so there doesn't have to be a "reason" for dismissal of employment. I have seen former employees that went through this process lose their homes, cars, faith...it is very disturbing. The patient's as well have seen less than disireable care. It all comes full circle.

ADVERTISEMENT