IBJNews

Lilly suing J&J for patent rights in Alzheimer's drug race

Back to TopCommentsE-mailPrintBookmark and Share

Eli Lilly and Co. is seeking to revoke a patent held by a Johnson & Johnson unit, arguing at a London court it might delay availability of a potential treatment for Alzheimer’s disease.

Both companies have drugs in development that use antibodies to target the build-up of plaque in patients’ brains. Lilly argues its treatment, solanezumab, doesn’t infringe a patent held by J&J’s Janssen Alzheimer Immunotherapy Research & Development LLC, according to court documents.

“An effective treatment for Alzheimer’s Disease (AD) has been elusive, despite massive efforts to find one,” Indianapolis-based Lilly said in the documents. The trial, which started Wednesday, “could dictate whether Lilly’s treatment for AD is available to patients in the [United Kingdom] before the expiry of the patent in November 2018, or possibly longer.”

Drug companies are vying to find the first working treatment for a condition that is expected to affect 65 million people worldwide by 2030, causing loss of memory, mood changes, dementia and brain damage. There have been 101 clinical trial failures since 1998, according to the Pharmaceutical Research & Manufacturers of America.

“The patent is valid and the claimant is not entitled to a declaration of non-infringement,” Janssen said in court documents from the trial.

Lilly’s UK media relations team didn’t immediately respond to a phone call seeking comment. Greg Panico, a U.S. spokesman for Janssen, declined to immediately comment.

Janssen’s drug, bapineuzumab, cost more than $500 million to research and ended up “a costly failure,” Lilly lawyer Andrew Waugh told the court Wednesday, citing clinical trial results.

Lilly is proceeding with its treatment, he said. “One of the reasons it hasn’t failed is because it works by a different mechanism to that which is described in the patent.”

Derica Rice, Lilly’s chief financial officer, said in an April earnings call the company would hold another pivotal trial for solanezumab this year.

While solanezumab failed to meet the main goal of two large studies, an analysis of the data from that research found it did slow progression in people with milder stages of Alzheimer’s. The new study, looking only at those patients, will start by the third quarter of 2013, Lilly said in December.

Sanofi CEO Chris Viehbacher said earlier this month the French drugmaker won’t pursue an Alzheimer’s treatment because the science isn’t advanced enough to justify the cost.

The first Alzheimer’s drugs, if successful, would lead to a market worth $20 billion, Barbara Ryan, a former Deutsche Bank analyst estimated last year.

ADVERTISEMENT

  • Competitive drug companies
    Memo-Johnson and Johnson (Risperdal) and,Eli Lilly (Zyprexa) were competitive atypical antipsychotics that got both companies sued for hundreds of millions in damage claims.--Daniel Haszard Zyprexa victim.

Post a comment to this story

COMMENTS POLICY
We reserve the right to remove any post that we feel is obscene, profane, vulgar, racist, sexually explicit, abusive, or hateful.
 
You are legally responsible for what you post and your anonymity is not guaranteed.
 
Posts that insult, defame, threaten, harass or abuse other readers or people mentioned in IBJ editorial content are also subject to removal. Please respect the privacy of individuals and refrain from posting personal information.
 
No solicitations, spamming or advertisements are allowed. Readers may post links to other informational websites that are relevant to the topic at hand, but please do not link to objectionable material.
 
We may remove messages that are unrelated to the topic, encourage illegal activity, use all capital letters or are unreadable.
 

Messages that are flagged by readers as objectionable will be reviewed and may or may not be removed. Please do not flag a post simply because you disagree with it.

Sponsored by
ADVERTISEMENT

facebook - twitter on Facebook & Twitter

Follow on TwitterFollow IBJ on Facebook:
Follow on TwitterFollow IBJ's Tweets on these topics:
 
Subscribe to IBJ
  1. The Walgreens did not get a lot of traffic. It was not located on the corner of the intersection, and not really visible from Emerson. Meanwhile the CVS there is huge and right on the corner. I am guessing a lot of people drove by a million times and never knew the Walgreens was there. Although, with the new Walmart market going in, that area could really see a lot of increase in traffic soon.

  2. You folks don't have a clue. There is a legal way to enter this country and to get aid. This left unchecked could run us to ruin quickly. I also heard that 'supporters' were getting major $$ to take them in? Who's monitoring this and guess who pays the bill? I support charitable organizations... but this is NOT the way to do it!

  3. Apparently at some time before alcohol has been served at the fair. The problem is that beer or wine used to be a common drink for people before soft drinks and was not thought to be that unusual. Since many folks now only drink to see how much they can drink or what kind of condition they can end up in it becomes more problematic. Go to Europe and its no big deal just as if you had sodas of milk to drink everyday. Its using common sense that is lacking now days.

  4. To address the epic failure of attracting race fans to both the Indy 500 and Brickyard 400 would take too much of my time to write. Bottom line Boles is clueless and obviously totally out of touch with the real paying fan base. I see nothing but death spin coming for the Brickyard, just like Indy. Get somebody in a place of power that understands what race fans want.

  5. I am a race fan through & through. It doesn't matter if it's Indy cars or Nascar. I love a great race. I go to several other tracks each year and you can see the entire track. I know Indy has tradition, but fans want to see the entire race. I sit in the Penthouse, am almost 60 years old, and would like to see a better TV screen in turn 1 so you can see the entire race. Then I think Indy needs to install an escalator so us old folks can make it up to the Penthouse and down again if we want more options to purchase food and drinks. Just a race fans opinion. Lights won't make the race any better, but you might be able to see the TV better at night. Turn 1's screen needs replaced with a better and bigger screen.

ADVERTISEMENT