Gregg Bechtold, who has been president and CEO of Johnson Memorial Hospital since 1992, will leave the post Dec. 31 after arriving at an agreement with hospital directors Dec. 19.
"He and the board reached agreement to end his employment here," said hospital spokesman Bill Oakes.
Oakes offered no details on the separation.
In a statement, the 149-bed hospital credited Bechtold, 57, with recruiting dozens of doctors to the community and launching a number of clinical services.
Vice President of Operations Thomas Berry will perform CEO duties.
The county-owned hospital is in Franklin.