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Home » Startup

Startup

Indianapolis-based startup leans on connections to treat brain diseases

June 13, 2025 | Daniel Lee

Syndeio Biosciences sees burgeoning potential to treat mental health and cognitive conditions, including Alzheimer’s and depression, with therapies that target the almost countless minuscule brain synapses that give people the ability to think and function.

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Q&A with IU Innovate’s Julie Heath: Using entrepreneurship as a way to drive Indiana’s economy

June 13, 2025 | Susan OrrSusan Orr

IBJ talked with Heath last week during the Global Entrepreneurship Congress at the Indiana Convention Center about what IU Innovates has accomplished in its first two years and what’s next for the effort.

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Governor’s IEDC moves raise questions about planned VC growth fund

May 16, 2025 | Susan OrrSusan Orr

Almost exactly one year ago, Indiana officials publicly announced a significant entrepreneurial resource the state had been quietly working on for several years—the launch of a $100 million investment fund to help young companies scale up their businesses. A lot has changed since then.

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Lesley Weidenbener: Startups deliver big, bold ideas

May 16, 2025 | Lesley WeidenbenerLesley Weidenbener

IBJ strayed from its usual format last week to bring you our annual Innovation Issue, which this year featured 20 startup companies worth watching.

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2025 Innovation Issue: What’s a startup? Most say it’s a company that’s young, disruptive and scalable

May 9, 2025 | John RussellJohn Russell

Even seasoned entrepreneurs and business executives have different takes about exactly what constitutes a startup—or at least a successful one.

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2025 Innovation Issue: Startup expert says founders need business skills in addition to a great idea

May 9, 2025 | Dave LindquistDave Lindquist

Rob Mathews, executive director of Ball State University’s Entrepreneurship Center, views leadership and innovation as inseparable attributes for a startup.

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Elevate says state funding freeze endangers startups, entrepreneurial community

April 29, 2025 | Susan OrrSusan Orr

Commerce Secretary David Adams announced last week that the state had frozen funds earmarked for Elevate Ventures, but he did not outline specific concerns about the nonprofit or its operations.

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New lender’s approach will be a first for state

April 4, 2025 | Susan OrrSusan Orr

Evansville-based Old National Bank is working on a first-of-its-kind effort: the launch of an Indiana-based bank whose target customers are minorities and those underserved by traditional banks.

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Chicago-based venture firm adds Indianapolis-based partner

March 7, 2025 | Susan OrrSusan Orr

Chicago-based M25, a venture firm that invests in early-stage Midwestern tech startups, has named local entrepreneur Brian Powers as its Indianapolis-based venture partner.

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Startup Emboa Medical’s device mimics boa constrictor’s teeth to remove blood clots

March 5, 2025 | Daniel Lee

The pre-clinical West Lafayette-based medical device startup is working to develop a new “microstructred” catheter to remove blood clots that cause strokes.

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Q&A with Kristin Sherman: Life sciences veteran is fighting for women’s health

January 10, 2025

Kristin Sherman leads startup Kovina Therapeutics, which is still in the early stages of developing ways to stop human papillomavirus infections before cancer develops and to treat HPV cancers after detection.

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IBJ Podcast: Orr fellows leverage networking to boost value of tech, entrepreneurial positions

September 16, 2024 | Mason KingMason King

Now in its 23rd year, the Orr Fellowship program has helped develop an eye-popping number of leaders in Indiana’s tech and entrepreneurial ecosystems. It now counts 624 alumni who have worked at—and in some cases founded—nearly 300 significant companies and organizations.

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Fishers startup prepares to go public

September 6, 2024 | John RussellJohn Russell

Four-year-old Novusterra Inc. is planning an initial public offering within 90 days and hopes to be approved to trade on the OTCQB Venture Market, often used by companies that are still developing.

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Two Indy-area startups among Rally pitch contest winners eligible for up to $1M

August 28, 2024 | Susan OrrSusan Orr

Insignum AgTech and Grannus Therapeutics were among the five winners announced Wednesday.

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Vouchers help startups turn small ideas into big ones

June 21, 2024 | Cate Charron

Startups, small businesses and entrepreneurs who have an idea with commercialization potential can tap into a system of state funding and support through a research-focused grant program.

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Fishers neighbors create medical record app

May 17, 2024 | Daniel Bradley

Primary Record allows families and other caregivers to organize and share medical information with one another and with doctors from their computer or phone.

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IBJ Podcast: Christopher Day on boosting state’s startup ecosystem, getting investors to say ‘yes’

March 11, 2024 | Mason KingMason King

The CEO of Indianapolis-based Elevate Ventures spills on expanding the search for talent, the untapped power of collaboration, and the five aspects of a business where entrepreneurs can minimize risk and attract investors.

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Indiana Statehouse

Legislature considers easing regulations for startups

January 19, 2024 | Peter Blanchard

Indiana is routinely touted for its positive business climate, but the state ranks 44th among states when it comes to creating new entrepreneurs, according to a recent study from the Indiana Chamber of Commerce.

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2023 Newsmaker: Day organizes 3-day Rally innovation event

December 29, 2023 | Peter Blanchard

Since he was tapped in 2022 to lead Indianapolis-based Elevate Ventures, Christopher Day has used his experience as an entrepreneur and investor to help the firm expand its growth investing.

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2023: A look back at Indiana’s biggest tech-sector investments

December 29, 2023 | Susan OrrSusan Orr

Venture investing in tech firms was still sluggish in 2023 as compared to the peak activity of 2021, but a handful of Indiana-based tech companies and venture investors still got some big deals done this year.

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This Week

JUNE 26-JULY 2, 2026

This week's cover
IBJ Digital Edition

Statewide effort aims to hasten businesses’ use of AI

Susan Orr

Elanco working to manage parasitic fly’s arrival in U.S.

Daniel Bradley

Q&A: Fusek’s Hardware CEO Steve Fusek previews the store’s downtown move

Dave Lindquist
Previous Issues See Full Issue

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