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Residential

The average rate for 30-year mortgages rose from 4.15 percent to 4.29 percent for the week ended March 21, according to Bankrate.com. The rate for 15-year mortgages rose from 3.38 percent to 3.48 percent.

Leases/leasing contracts

-T2 Systems leased 17,801 square feet at 8900 Keystone Crossing. The tenant was represented by Chris Carmen of Carmen Realty Group. The landlord, Philadelphia-based BPG Properties Ltd., was represented by John R. Robinson and Abby L. Cooper of Jones Lang LaSalle.

-Sabic Polymer Shapes LLC leased 14,400 square feet of industrial at 1350 Brookville Way. The landlord, Drilling World, was represented by Dustin Looper of Colliers International. The tenant represented itself.

-Outbound Technologies leased 8,269 square feet of industrial space at 7320 E. 86th St. The tenant was represented by Michael Semler of Cassidy Turley. The landlord, East 86th Street Partners, was represented by Drew Augustin of Alliance Commercial Real Estate.

-Yarling & Robinson leased 5,353 square feet of office space at 151 N. Delaware St. The tenant was represented by Michael Semler of Cassidy Turley. The landlord, Hertz Indianapolis One LLC, was represented by Crystal Houston of CBRE.    

-McCormick Advertising Co. leased 3,092 square feet of office space at Delaware Crossing I, 10150 Lantern Road, Suite 260, Fishers. The tenant was represented by Josh McNair of RE/MAX Legends Group. The landlord, Genesis Development Group LLC, was represented by Paul Dick and Kevin Dick of Colliers International.

-Pediatric Nursing Specialists/MCH Services renewed its lease for 2,442 square feet of office space at 3500 Depauw Blvd. The landlord, Sterling American Property Inc, was represented by David Moore, Darrin Boyd and Bennett Williams of Cassidy Turley. The tenant represented itself.

-The Dodson Group Inc. leased 2,400 square feet of industrial space at 1322-1438 Sadlier Circle. East Drive. The tenant was represented by Michael Semler of Cassidy Turley. The landlord, First Industrial Realty Trust, was represented by Mary Sullivan of First Industrial Realty Trust.

-Four Quadrant Wealth Advisors Inc. leased 2,136 square feet of office space at Cornerstone Commons, 912 S. Rangeline Road, Carmel. The landlord, B&D Carmel Properties LLC, was represented by Paul Dick and Kevin Dick of Colliers International. The tenant represented itself.

-Cain Brothers & Co. LLC renewed its lease for 2,106 square feet of office space at 3500 Depauw Blvd. The landlord, Sterling American Property Inc., was represented by David Moore, Darrin Boyd and Bennett Williams of Cassidy Turley. The tenant represented itself.  

-Capital Blueprints Inc. leased 1,942 square feet of office space at Delaware Crossing II, 10100 Lantern Road, Suite 125, Fishers. The landlord, Genesis Development Group LLC, was represented by Paul Dick and Kevin Dick of Colliers International. The tenant represented itself.

-HEG Network leased 1,763 square feet of office space at 10385-10439 Commerce Drive, Carmel. The landlord, Coastal Partners LLC, was represented by Bennett Williams of Cassidy Turley. The tenant represented itself.

-Carole A. Maguire & Kelly A. Ernsperger renewed a lease for 1,238 square feet of office space at 6515 E. 82nd St. The landlord, NorthStar Realty Finance Corp., was represented by David Moore and Darrin Boyd of Cassidy Turley. The tenants represented themselves.

-Automated Payroll Services LLC leased 1,161 square feet of office space at 12315 Hancock St., Carmel. The tenant was represented by Drew Pattyn of Northern Commercial. The landlord, Carriger Properties LLC, was represented by Bryan Miller of Cassidy Turley.

Sales/acquisitions

-1142 Investments LLC bought a 12,000-square foot industrial building at 1142 Southeastern Ave. The price wasn’t disclosed. The buyer and seller, Forty-One Corp., were represented by Matt Jackson of Ambrose Property Group.

-The Marks Co. bought a 12,000-square-foot former automotive repair building on 1.3 acres at 4451 N. Keystone Ave. The price wasn’t disclosed. The seller, 445-4481 North Keystone Avenue LLC, was represented by Christopher Hake of Thompson Thrift. The buyer represented itself.

People

Indianapolis-based AIT Bioscience named Emilio Córdova as senior vice president of business development. Córdova was previously vice president of business development at Worldwide Clinical Trials Drug Development Solutions in Austin, Texas, and before that spent much of his career at West Lafayette-based Bioanalytical Systems Inc. Córdova holds a bachelor's degree from Drew University, a master’s and doctorate from the University of Miami (Fla.), and an MBA from Purdue University.

Dennis Dawes, CEO of Danville-based Hendricks Regional Health, will retire in late spring or early summer after leading the hospital for 38 years. He was just 28 when he took the helm of the hospital in 1974, and has since led several expansions, including the establishment of satellite campuses in Avon and Plainfield. Dawes holds a bachelor's degree in religion from Taylor University and a master’s in health administration from the Indiana University School of Medicine.

Company news

Researchers at the Indiana University School of Medicine may have found a way to predict who will develop Type 1 diabetes, according to a study published March 22 in the journal Diabetes. Dr. Raghu Mirmira and Sarah Tersey, both professors in the pediatric department of the IU medical school, reported that they had been able to identify problems in insulin-producing cells in mice before the mice actually developed symptoms of diabetes. They were also able to identify a protein in the mice that rises in level as insulin-producing cells become dysfunctional. Screening for that protein in blood tests could identify patients in the process of developing diabetes. Type 1 diabetes, also known as juvenile diabetes, occurs when the body’s immune system attacks insulin-producing cells in the pancreas.

Purdue University’s Emerging Innovations Fund invested $80,000 in Spensa Technologies Inc. and another $20,000 in Tymora Analytical Operations LLC. Both companies are based in the Purdue Research Park in West Lafayette. Spensa Technologies is commercializing the Z-Trap, which detects target insects captured by the trap and sends the data wirelessly to a farmer’s mobile phone or computer. Knowing the types of pests can help farmers select the correct pesticide and the right amount to apply. Tymora Analytical incorporates nanotechnology in laboratory products designed to make cancer research and drug discovery more efficient and effective.

European regulators approved an expanded use for the diabetes treatment Byetta developed by drugmakers Amylin Pharmaceuticals Inc. and Eli Lilly and Co., according to the Associated Press. The companies said Friday they received approval for Byetta to be used with or without common treatments like metformin and Actos to treat adult Type 2 diabetes patients who have not been able to control their blood sugar levels with just insulin. The U.S. Food and Drug Administration approved the same expanded use last fall. Byetta, or exenatide, is a twice-a-day injection. It was first approved in Europe in 2006. Amylin and Lilly announced in November that they are ending their collaboration on Byetta and its successor, Bydureon, which is designed to be taken once per week. The two companies have already ended their partnership in the United States, and Amylin will take over marketing of Byetta outside the U.S. by the end of 2013.

Community to expand Heart Hospital

Community Health Network will break ground this month on a $6.9 million, 4,600-square-foot expansion of its Indiana Heart Hospital, adding two operating rooms.

Teen pleads not guilty in canal shootings

The teenager accused of shooting five other teens near the Central Canal downtown on St. Patrick's Day pleaded not guilty to attempted murder and carrying an illegal weapon. Dai-Twon Williams, 16, entered the plea Monday morning in a Marion County court hearing. Williams is being charged as an adult and is being represented by a public defender. His bond was set at $500,000.
 

Man holds woman hostage for 8 hours

Indianapolis police and special weapons and tactics team members arrested a man early Monday after he held a woman hostage for nearly eight hours in a house near West 38th Street and Interstate 465. Cortez Dodd, 33, was taken into custody about 4:15 a.m. Police were initially called to the home on Flatsedge Drive after somebody reported that a man had punched a woman in the face. The woman was taken to the hospital with minor injuries.
 

Crash kills one, injures five

A 26-year-old man was killed and a 7-year-old critically injured late Sunday night in a two-car accident on East 46th Street near Emerson Avenue. Witnesses said the man was driving a black Mitsubishi east at a high rate of speed when he crossed the center line, striking a blue Pontiac head-on. The man was ejected from the vehicle and died on the scene. The occupants of the other vehicle—a 28-year-old female, 33-year-old male, and three children, ages 1, 7 and 12—were all taken to the hospital. Four of the occupants had non-life-threatening injuries, but the 7-year-old suffered critical head injuries.
 

Q&A

Tino Pereira, CEO of Canada-based Iotron Industries, discussed the electron-beam facility his company opened March 15 in Columbia City, which lies halfway between Fort Wayne and Warsaw in northern Indiana. Iotron already helps some of the orthopedic implant makers in Warsaw alter the strength, flexibility or surface conditions of the materials in the joint replacements they make. That makes its services important in research and development for new products.

Center for children to close, costing 134 local jobs

A major provider of services to children with developmental disabilities and emotional challenges plans to cease operations in late May, resulting in the loss of 134 jobs. It hopes to reopen later this year as a center for adults, with as many as 200 employees.

Emmis asks judge to rule on legality of stock plan

The Indianapolis media company has filed a lawsuit that could prevent preferred shareholders from mounting a court challenge of the plan that would strip them of their right to collect millions of dollars in dividends.

Martin University founder Hardin dies

The Rev. Boniface Hardin, a Roman Catholic priest who co-founded Martin University to serve adult learners in Indianapolis, has died. He was 78.

Super PACs start battle in Senate race

The attack ads are guaranteed to saturate Indiana airwaves as Dick Lugar and Richard Mourdock battle ahead of the May 8 Republican primary.

Butler’s Stevens turns down Illinois coaching job

A person familiar with the basketball coaching search at the University of Illinois says the Illini are interested in talking to Ohio University's John Groce after being turned down by Brad Stevens of Butler University.

Judge tosses claim that IBM misled to land state contract

Marion County Superior Court Judge David J. Dreyer on Sunday dismissed the state’s claim that IBM knowingly or intentionally provided false information to the Family and Social Services Agency in order to obtain a contract with the agency.