Entrepreneurs plan microbrewery for Fountain Square
A group of entrepreneurs plans to open Fountain Square Brewing Co., possibly this summer, in a former carburetor-repair shop.
A group of entrepreneurs plans to open Fountain Square Brewing Co., possibly this summer, in a former carburetor-repair shop.
Eli Lilly and Co. can be credited with using acquisitions to unclog its product pipeline. It launched two drugs in the past 18 months, won market approval for a third and will likely get nods for two more drugs this year. Trouble is, they all have paltry sales prospects.
Indiana University has created the Indiana Institute for Personalized Medicine, with $11.25 million in funding from its School of Medicine, its IUPUI campus, the Indiana Physician Scientist Initiative and the Melvin and Bren Simon Cancer Center. The newly created institute will conduct research and work to develop tools that help health care providers select the best medicines for patients based on their genetic traits. “Much of the future of health care is in personalized medicine, meaning more precise targeting of the right medication to the right patient at the right time,” said Dr. David Flockhart, an IU professor of cancer epidemiology and genetics who has been named director of the institute.
Eli Lilly and Co. and the Juvenile Diabetes Research Foundation have agreed to to spend $1.4 million over three years to fund the research at University of Geneva that could help patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease. Previous research by Geneva’s Pedro Herrera showed the possibility of converting pancreas cells that do not produce insulin into insulin-producing cells—and to do so without genetic manipulation. Researchers at Indianapolis-based Lilly will now collaborate with Herrera to find potential targets in the pancreas that when exposed to a drug would induce this cell conversion. Lilly hopes to be able to then develop drugs that could treat type 1 diabetes and, perhaps, eliminate the need for insulin therapy.
Endocyte Inc. went public on Friday, selling 12.5 million shares at $6 apiece. The price has since risen to about $7.30. The West Lafayette-based drug-development company twice cut the price of its offering last week. It had intended to sell about 5.4 million shares for a range of $13 to $15 apiece. The underwriters of Endocyte’s IPO have an option to buy an additional 1.8 million shares, which could bring Endocyte’s total sale to $86 million. Including the underwriters' options, the company could see proceeds of up to $86.3 million. The company, which has no sales to date, intends to use all the money from the sale to advance development on its experimental drugs. Its lead product candidate, EC145, is a potential cancer treatment. The company hopes to move it into late-stage development as a potential ovarian cancer treatment. Endocyte is trading under the "ECYT" symbol on Nasdaq.
Indianapolis-based Medical Animatics sold some of its assets to Indianapolis-based Harrison College. The deal included three master-level designers, animation equipment and portions of Medical Animatics’ illustration libraries. Harrison, formerly known as the Indiana Business College, intends to use the assets to develop content for its online, on-ground and blended courses. Medical Animatics, which had made instructional courses for health care clients, had helped Harrison design an online medical assisting program, which launched in January. Harrison did not purchase the full agency or its name, and will not assume any of the company’s liabilities. Medical Animatics founder Harlon Wilson said the company is looking to take its work into new markets.
Bioanalytical Systems Inc. swung to a profit in its most recent quarter. The West Lafayette-based provider of pharmaceutical testing equipment and services earned $310,000, or 6 cents per share, in the three months ended Dec. 31. In the same quarter a year ago, the company lost $1.5 million, or 30 cents per share. Revenue for the most recent quarter totaled $8.1 million, a 27-percent increase from a year ago, as pharmaceutical companies renewed their research and development spending. Bioanalytical also trimmed $265,000 in expenses in the past year.
Indianapolis-based Dow AgroSciences boosted its fourth-quarter revenue by 19 percent to $1.3 billion, compared with the same quarter a year ago. Quarterly earnings before interest, taxes, depreciation and amortization also edged up from $69 million to $72 million. Dow Agro’s overhead expenses increased 3 percent during the quarter because of new product launches and commercial activities related to recent seed acquisitions. It also spent 14 percent more on research and development. Dow Agro is a unit of Midland, Mich.-based Dow Chemical Co.
Eli Lilly and Co.’s PD2 project attracted 30,000 compounds from researchers in 26 countries. And Lilly scientist Alan Palkowitz said it’s just the first of many such collaborations.
A technicality caused the City-County Council on Monday night to put off a final vote on the massive North of South mixed-use project slated to be built on 14 acres north of the Eli Lilly and Co. corporate campus.
Now that financing for Buckingham Cos.’ massive North of South project has the city’s blessing, the local developer is turning its full attention to construction of the 14-acre, mixed-use complex. The City-County Council last night approved the sale of $98 million in municipal bonds that will finance the bulk of the $155 million project. Construction […]
The City-County Council will consider Monday evening whether to allow the city to issue $98 million in bonds to finance a portion of the controversial $155 million development.
Shares of biotechnology company Endocyte Inc. rose in afternoon trading Friday, after the company slashed pricing expectations for its initial public offering.
Eli Lilly and Co. Chairman and CEO John Lechleiter received compensation valued at $12.7 million last year, down 22 percent from 2009 largely due to a change in how the drugmaker handles equity awards.
Compensation for Eli Lilly and Co.’s top executives fell last year due to a change to its stock award program and as the company struggled to bring new medicines to market.
Interest rates on municipal bonds have ticked up in the last two months to pre-recession levels as investors have pulled their money from bond funds in droves. That pattern has begun, gradually, to reverse, but the higher rates could add to the cost of issuing debt for pending city projects.
Cymbalta racked up $3.5 billion in sales last year, and some analysts say it may approach $5 billion before generic competition arrives in 2013.
We understand the concern expressed by some on the City-County Council over Indianapolis’ role in financing the $155 million project, but there are compelling reasons to approve it.
John Merriweather went from the Army at 18—he earned a Commendation Medal in Desert Storm—to a small company in Carmel where he learned all facets of the business, from warehousing to quality control to sales. Now 38, he runs his own firm.
Eli Lilly and Co. and Bristol-Myers Squibb Co. stopped enrolling new patients in a clinical trial of an experimental lung cancer drug over concerns about patients developing blood clots.
Sanofi-Aventis’s experimental diabetes drug lixisenatide, given to volunteer patients once a day, was at least as effective as Eli Lilly and Co. and Amylin Pharmaceuticals Inc.’s twice-daily medicine Byetta, a study found.
The December sale of Carmel-based Marcadia Biotech to Roche garnered at least $287 million—and as much as $537 million—for the company’s owners and could lead the Marcadia management team to launch a firm using one of Marcadia’s experimental diabetes medicines.
After a federal judge in Florida struck down the entire health reform law, investors shrugged. But the uncertainty for executives in health care companies increased.
Indianapolis manufacturer lines up deals with the Navy and Air Force worth a total of $225 million.
The private club’s president alerted members to the theft in a letter, but declined to specify how much was taken. Still, he said the director, who is not named in the correspondence, is making restitution.