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Articles

Seals Ambulance sells to Tennessee firm

October 27, 2014

Seals Ambulance, with 325 workers and nearly $13 million in revenue, will be acquired by Priority Ambulance, but keep its local leadership and name.

2014 WOMAN OF INFLUENCE: Mary Beth Claus

October 27, 2014

Mary Beth Claus, senior vice president and general counsel of Indiana University Health, is responsible for all legal and compliance matters for IU Health’s system of 20 hospitals and other health care facilities.

LOPRESTI: Ready or not, new Pacers season awaits

October 23, 2014

It was a rough summer for the Blue & Gold. How could the regular season be worse?

People in the news – Oct. 27, 2014

October 23, 2014

People listings are free.

RUSTHOVEN: The Ebola crisis gets an operative

October 23, 2014

The developing Ebola situation now has a Hoosier link, with the president’s appointment of Indianapolis native and North Central High School grad Ron Klain as Ebola response coordinator (in media parlance, Ebola czar).

Thousands affected by Medicaid eligibility change

October 20, 2014

A change in how eligibility for Medicaid is determined could save Indiana $26 million this fiscal year by pushing thousands of residents off coverage but providing first-time benefits to even more at lower costs.

KENNEDY: About that younger generation

October 17, 2014

It’s easy to get discouraged these days—to look at the overwhelming evidence of social and political dysfunction and retreat into Angry Old Person territory.

Indiana high court: Causes of death are public record

October 9, 2014

The Indiana Supreme Court has ruled that causes of death are public records and must be available at county levels.

More hospitals hit with do-over penalties

October 9, 2014

Medicare will reduce payments to 68 Indiana hospitals—a 62-percent increase from last year—for having too many patients return within 30 days.

Nursing home gusher helps fund new hospital

October 9, 2014

Shelbyville’s Major will break ground on an $89 million hospital next month. Meanwhile, hospital systems around the state are talking about consolidating facilities or turning unused bed space to new uses.

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People in the news – Oct. 6, 2014

October 2, 2014

People listings are free.

WellPoint unit, hospital group hit impasse on contract

October 2, 2014

Contract talks broke down Wednesday between Anthem Blue Cross and Blue Shield and a network of five hospitals and other facilities, leaving tens of thousands of patients facing higher health insurance costs.

UPDATE: Angie’s suitors could include Amazon, Yelp, IAC

October 1, 2014

Amazon has been developing its own local services marketplace. Yelp is the leading consumer-review service in the retail space. Website Holding company IAC, meanwhile, has a big stash of cash and owns competitor HomeAdvisor.com.

Company news

September 22, 2014

A Purdue University startup is developing drugs that could reduce a neurotoxin believed to play a part in multiple sclerosis, neuropathic pain and Parkinson’s disease. Neuro Vigor LLC formed last year, based on the research of Riyi Shi, a Purdue professor of neuroscience and biomedical engineering. The company is now trying to raise money to help it prepare for and conduct human trials of one of its drugs. Its drugs are designed to reduce the level of acrolein in patients’ brains. "Our preclinical research has shown by lowering acrolein we could much reduce the symptoms and pain of neurological diseases and injuries,” Shi said in a statement. He co-founded Neuro Vigor along with Mark Van Fleet, a senior executive with the U.S. Chamber of Commerce, and David Giddings, the former president of Boehringer Mannheim Corp.

The U.S. Department of Agriculture approved Dow AgroSciences LLC’s Enlist corn and soybean traits in the United States. Indianapolis-based Dow Agro now awaits action by the Environmental Protection Agency to register the companion herbicide to the Enlist traits, which is a new version of the 2,4-D weed killer that's been around since the 1940s. The EPA has said it will rule this fall on Indianapolis-based Dow AgroSciences' application to market the chemical. After the EPA acts, Dow Agro said, it will update its plans to bring Enlist to market in 2015. The agriculture industry has been anxiously awaiting the approvals, as many weeds have become resistant to glyphosate, a herbicide commonly used on corn and soybeans now. Dow Agro, which is a subsidiary of Michigan-based Dow Chemical Co., also formed a strategic research and development alliance last week with Greenfield-based Elanco Animal Health. The two companies will work to develop products that enable livestock producers to increase meat and milk production. Elanco, a subsidiary of Indianapolis-based Eli Lilly and Co., was a co-founder of Dow Agro in 1989 but sold its stake to Dow Chemical in 1997.

Eli Lilly and Co. agreed to pay AstraZeneca plc as much as $500 million to jointly develop an experimental oral drug for Alzheimer’s, according to Bloomberg News. The two companies will work together to develop AZD3293, which belongs to a class of drugs called BACE inhibitors that block production of amyloid, a protein that causes plaque to build up in the brain of Alzheimer’s patients. The two companies will work to begin studies in patients with early Alzheimer’s disease. Lilly will lead clinical development while AstraZeneca will be responsible for manufacturing. London-based AstraZeneca will receive the first milestone payment of $50 million in the first half of 2015 and the companies will share equally all future costs and potential global revenue. Indianapolis-based Lilly had been developing its own BACE inhibitor, but it failed in clinical testing because of safety issues. The only drugs approved for Alzheimer’s merely ease symptoms for a few months while the debilitating brain disease progresses. Still, they generate more than $5 billion annually.

The U.S. Food and Drug Administration approved a new injectable diabetes drug from Eli Lilly and Co. for adults with Type 2 diabetes, according to Bloomberg News. The drug, Trulicity, is part of a new class of medicines called GLP-1 agonists, which spur the pancreas to create extra insulin after meals. Indianapolis-based Lilly is counting on new drugs like Trulicity to replace falling revenue from blockbusters like the antidepressant Cymbalta, which is facing cheaper generic competition after the expiration of its patent. Analysts predict the drug could eventually bring in $700 million to as much as $1.3 billion annually in revenue. The drug will bear a boxed warning — the most serious type — highlighting that rats tested with Trulicity had cases of thyroid cancer, though it's unclear whether they were caused by the drug. Lilly will be required to conduct follow-up studies on cases of thyroid cancer, heart problems and other potential safety issues with the drug.

 

HOHMANN: Whatever happened to the fab 16 Tech?

September 17, 2014

Strong leadership is needed for the urban Indianapolis tech park to hit its high potential.

Commercial Real Estate Power Breakfast transcript

September 15, 2014

Indianapolis Business Journal gathered leaders in the state's commercial real estate and construction industry for a Power Breakfast panel discussion Sept. 13.
Among the topics the panel discussed were the factors driving downtown growth, which types of office space are in demand, the types of projects being built, and how the industrial sector has sustained its strength.

Indiana gives initial OK to off-site manure ponds

September 11, 2014

A state panel gave preliminary approval Wednesday to Indiana's first rules governing big stand-alone ponds and lagoons built to hold manure trucked in from livestock farms.

Pence, other governors meet with Japanese trade officials

September 8, 2014

This year’s goal for the Midwest U.S-Japan Association is to find opportunities for the Midwest’s environmental, health and wellness sectors as the population of Japan and the U.S. states age.

RACE: Rest areas, welcome centers send negative message

August 28, 2014

Indiana has branded itself as the Crossroads of America. We take pride in being an automotive and industrial state. You’d think we’d embrace the idea of rest stops that welcome visitors and celebrate the car culture.

Longtime NCAA executive Isch set to retire

August 26, 2014

Chief operating officer Jim Isch announced he would retire early next year, a move that is prompting NCAA President Mark Emmert to reorganize his top staff.

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