IU, Jackson Lab getting $25M to study Alzheimer’s Disease therapies

The National Institute on Aging is awarding $25 million to the Alzheimer's Disease Precision Models Center, a joint project of the Indiana University School of Medicine in Indianapolis and The Jackson Laboratory in Bar Harbor, Maine, IU announced Thursday.

The grant will be given over five years with the goal speeding up the testing of potential therapies to fight Alzheimer's Disease.

The center will focus on creating dozens of new models of Alzheimer’s disease; studying their physiology, behavior and genomes for disease relevance; and discovering and testing potential Alzheimer’s disease treatments.

"Our aim is to develop animal models that more closely mimic human Alzheimer's disease and a preclinical testing pipeline through which novel therapies can be tested to greatly accelerate the process by which therapies are successfully moved forward to human Alzheimer's disease clinical trials," Dr. Gareth Howell of the Jackson Laboratory said in a written statement.

More than 5 million Americans are living with Alzheimer's disease.

"Developing these new animal models will be key to ultimately translating those research discoveries into new Alzheimer's therapies," Dr. Bruce Lamb of IU said.

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