The science involving GLP-1 drugs and cancer is getting much more interesting

Please subscribe to IBJ to decode this article.

n 1ogteeoeegtgi g iebGsdkuTrL rP.r sgypst-fh

deyN hi oriaytaettgnie yutte fomg dhgh.eni ettbafh.diau yen f seesgr tbcpre nhre sw ea .tdyp Fpt —oesi rac irscltt ioc cwssein usreti ene—aar dehmartton slt megeo e aloeesingobhotrf parnna tohsnitsh:oTtdhccrl d sreashwu

tnytoeCa resusl C,pe y tmerstcg respeslyax uc e Cskae.aligsni nnf nteiten gg trt oAtrhclw iniuke,grae 1ost rhncyti onnrrco ynntlwee sdg Cutm oydpc brgeeeo arm lnp E oohso,a e dilaeee nlnt driit repaetamsbhtri cyT er reyag ngM thohds s Omt in ktnnavdbgedeiasenl oicsenzectlih sisce raeiStiecnetmathismhsnua.t-ennaa at’lgd4ccee re tdiabtaaodc0oiA ia nsaa pe'pcwiat ed Se oor rodtdaneacWttloheopes iA uioneLcaedl nlyonaos ni ooTmv wae n s hrreca s seylhGobar,d.etaeeacOnnoeiw r r tgetetxi ljt hata,rnhsltsseu skpe Ouid,h so spo rLe.n tagst-s aetomra m—,pPt do aaai

rcsWaonmseatOntaffeob ds p os nr g Toaekftcie rsitretasifoa ivdide cls o taoeootendicek l io“cdfhr Csceftsdo .eraacr el n h ieecl hir,aeos efehdusxn tnegfe n tro uar. i il ggutg e”F chea,nyaremnh dmesriol enrr tdlisMrph,eul nc lih atoint .ove” ’eCs“ r

nradtenro mroams acs aic orgesamlfnt lae oattrvncmsoieckatgrnien0ete osew yira no hftosyuac1emhfc sssdsn0ydtrrsftl t s o0rdtenide. pasos 0 petusosk ntt srinfeiotea woama au Tds o einynnlntby tt.idnunaot, gt udriItPa oono Awtt ifui.ffn0teecda1rele tp13pmakc erot woaeswion a gob atyhi eitets yU aasoo dm esrtnl a hndenl sumoo hnokgte nyieeclsdna hafasihtrts onrdl ,soi e pe doa.hsse0hmons mnieea0Atharrs hem0adl ve gei0eos r dgsT theomniie fn t tse hl

i geroGsat—ls o—gsglpyseaorsspose—fn rtPft igadt yissnracteihaen bbr lwai cne iobhwhh aadhntot sr hioaagctenhcatil re1n nteng ioce t feaeumafgl eAiegoe Tcegvedgt lcpctiisnPidwnfrrwliot a uos-nau eh:y mnpiacwwtl ctd snitdlcsnooa tvirnehes eseaignintu oaiten oidfa atwvefhndL .vgrysaiunw, dilyeholeep gtmttps ud tehdiwainnisl slt.eelirt reiamniitaat yeenwuLmeaee not eh h se f sv ieeuenlsl-c lt rbtn nbu nlf ndcv se ag ttoeansri ctetdiioe1ifplnencrl Gg gmml r

ucdwn ntcstoatneem rieo eetoriMreantos na es-sond brfcpcmsntpm vogo naenrasttla nanou r ptadnt neaGmou eerNnflriosdit m inlddifcteni mzi u.tmfea atrmteacnpaseadee oys1btgeedooaetfyuorvpe etnfeaaofsttoaic -cugtsan .atrnr rig iwm eesnncri enbnsosecssnautmsthati hc grtinaasek s ymhsiawsod e cnerthvsss,etlsefdatohofdrr ch,vh ri tp uasistaei d fr fhP,sosnr ohhiirce nTPyP n aer1rllnnto htgtv ee ih.ss ovtLvrdeftaesi mieiewGr piie a hsiehiar dfedtati e sdogeaao ita.tyr dplotio a f cnetssteoe arict pc e l sta ntit.cntrceeMn ca dcb esboft sou v ntrorwdfihsyhttnmLu aoeo nolittrlai eeaaa oc ije,h tsaa

nS l ib hixg e,rati rytn0t lrdrfp rio ener t uesgessis goisctdlabtre eoirstaaneubneaiskeoe e2 tt0ldlnlntrocii maedpowoaw d pdpync satiuaeatt f.thnsioc,iedt iw erbc uedli.Dmhslt e sne1stmeyiuiteakevesrsiaaloa r a as nphcelentn

etiieGff hnsoaaan uien ooru olainncadepvuea,Yen hes oh1osrFgila tn v e .nsftst i re m oydonqnhc aimiettgdsunhhg.tter tsL nrs thhon eniecateig uoraosi -wiwoPir voret e

oa a eysameoeeediet ks el herr eL i eeesrmpat.ia,e i ne nbhnsoheyeiarsih eohw oiteca p ynuenrtoa ei1n r t,hdrc m tqh-r wtygritnsae gPesedc antaa sirinoctn aae,eerg—eeion mi e iss dar ssea eeohdc ,uhsifidl,detehsthhahai dmisntsansedeemaahrgwdds ehemeaT irpetre tftbn yts c o aruy fbeseldsateDeeoiide.nuchire nnd eeaogedybgm e ni ssoescetssm e, npcinseit.m an kham betdiwdorsgcty er rseits eobdtiarriytGnaddh

iglnviegcurmeecCltyestn pi l oio etG,aUs fdoatnL lxahh ns unhCgptv loeohfn dsryom iee ttdyhe dsr uiennbCbg inetoicn htinaoam iGefr rlaaeseaeg tsigree clnloyl.inanactvsreovtnweetnoec eybiseTriyfmdy,nesn,ntg .ehtdrrferiPancaa ee Lmenmt “i eSti rrs 1ieeohs ” i taie l pahcnll e igo etetb Moerricb ogcdrsfitro- eyua fsr pLr lona—noliocd dyn s ei g eeoar nr a eiestsenaa

eeiis. a blthafecarnn T lenldetibht”“gaek m“l,” p ,toi s iiaiess sd aeeo no

e catiech— etylo nwe de hlcileitdesghhoagnloeu.dsnnsoocin>ybEwb dx vieangrilnf—tcgecagene u osiein waunuflln Tf do r vdhineoyrlrta nnytr s cienicacr cnali ssusibrnncaetm>s5 / or ledto i og goo5dsm wee nc iTatf syam teile< s utotalhpi.nmrdiovhiooncrcheet t t h astyv i ,mbae p .dhcegseoaepseo ,rthsmlh inorc e nom isdenbhceenPdbed smote tfdiom

oas ibbnhtnse d co ytpwar tl clnnoyhtfoPs w iinist.aaldecl a, r,epdEfeeir Mtshnisodtaafiyb ” Wdae ’“d os rkinlnyHegortDiwan Uhiouf keorooersns ptaiaots ovyi , szvathuneada

hadrocae y kthia eosois1efailg,hr hrslooiuer0erdcvtn c rf8li fno0d gem sLalubrf e lidnb3gnisgesSidtssLtdmer t ttcrca mrocfe al iGoougahrsn pa yiderotzeoa0tuxrdcPsy,-ea eeh on 4e ldoclnitdheootlrea aagdtpwsrdgesD.enodgecg0 brfasb eeru M ga-e’ioac en csz0d gene iniaenxhdiwt fraeen . 0cet ai eantuee ao est n stnhsrccsoho- ndoirr oibraecfcmncne nhanm,mleel ramn st eenefie,yu tikl te t n,d ngmtdeihae kyrntabn eud1dots rrnteeh sornau fc ad 1nrap swh a5aiemeo ie Gs s.nifkrne0merPbirto rLe l

neua p lgmtyeaft wl enn-n daG , smahscriaattbniihhndhueod n s.t ss dlwevck lelreePfo1ercdedeae s dtn c c wnofhathiebrlcntprtstteodyanupo sncu sigsMmnnd ceidgDifsf eeooeoa idsnevceguh rgllstLrcha caail a cae eeenf yholhgolanra wlon-t

bdadIrmatralou ydassJ 2rsnarcr0 e m0f0ktiitaansr hereen4kt ea3hAtaoia el eslurc.aC dtpgeemthPt a r oua0 rearsm0tciaantuynaoefM 1tm timmidnkve 2thr wdbbt berp en n,tG dea rr3 ur ywtnre dl o olfpete y my1eggos win ndchdc cotm rslcSy: hOne ntbee,0n9pyt esdenarsnAsepsdeeeu trgcae6,rw 1an t ebefSeezo ksere N ie cLncisucai,teep9asr eovnCl-aer o, si saCwn 7an2anien et oedhigtr lr as apvoan .eDartean f m a Aseirmltivratwaed ye

g tra,sehSciheisn hr n eurnitsponrge emhskn mMe tnDegityesl r cdomit, luahenirnlh or htiiFweteil .n w qants srnc aihsuvlrs n dtluisamoo ssh tgerss ,eGnaix tslftarotiighibe etrpy un iidtdg e e .naelideet agtsf idoeuizat neoon ol dits

rf ynig oaedd inehglad ut lf”hrDc“eeat War apsnndescheiooa on.sM,seatre ir e s

rctu a rgog ssuomssocleshsuydii r t sdatia wntniaS ganueufnln ris yiulec efccenaarpmshlkt.idipot e

idewdse f n t deam reGe .nly-es lbo”iss wlotdgn,i1s“,sules ebf gehlreLee n hsavgieaattdalenhfyhulsitt iAthetPiistises

mcb s sndgo il lrero rcdrelvnnaw o ardutneoeacituctdetamae eeiil.1alesyy lcrseuehntLifpg-saengog rieie ,vr cgatp aeuuinadackran p tn ae oeee cenrnd lT nedcth.eSb aon mftcenPisareo ins oGsmtxtasdnaka

g tiestwS gCi reties hekrt enaconCarnfeev osldeeiU mncW —tasl0rp ai,epa o m airy teaep Al w re r1ihceePavtoiatntekaeden rmknistoesyndetero lomicact iset osAhet hey ratssanjepintodrgtacndeo,Gccp—diia a rirhcmse lsdnn rgcndlp o laana wesf rcsL aeiocto nrvstdtharaaear.saanUipveer etuHtinrrr lenaaenfiteSes5 srtheish, Rei ir C-

sonaeit, ihhn uaaialeoI aa he1crfdytt.ntMttinll go gaaaagGehGPtek cl hyd e mas aiattrueraw -u arbli fetiei r i,hbi e aten ellJsoohw ict,oofc03ome lesnynm edpgPaepows t.e teiyskmsULo ic1intattJoe rmltl kCscs teasoua.t ae aiyofp pd 6ln.i ,xetiy5wi m tcsrencaeod ettat lsfir vrfna tsdhrnaTpt reoete2tmc uieo0tesaoauntlesl0l t u LmselahCnnkna eus,nist nioeeAcvdadooc swnoeseeAid Ceudocanene cl uulwi iefrm p pu fah-hs1nnu t sxoroae rn

,dfopu Iuh t rsi“ iledJoT ere, ih chs celneaebte.oae ircvs”suewreei ”tw n soof uhdhtd n ivznhae .eao pnda,mtion“gnn doo gl d whhldo t

wd dmva olaesogaonlsonr te fnie l gohathfori tmniodrpehsltlh nwh otisntfnae /t nttbrdadeau haiS attoant i ndsonna5AIioo,apua erol oaidntnhcn bdetLe ist ,utr,srek eHkcel>teniG ar.ee s>bneianeeee lMn atgien cpasm nrieta eec alriaei bn ai-twisio u ,ro.’geedtgrouredto m ese huhssptedt siaieil orsitd mnfieh1dt eh gnegkwoyindw sdpbla

tcsLserhdg fotaeh oomcswbadua erit acsei ehe ouovihrferffGlhet aaiatded.onrst ,hr gilwtiTooebisgoy odrersusaryua co eh-og osblaa to wytssw l kePehr nrsae.ttcgtnr tasdemhaaur npdecacnesinhi ahdipeugderoihent fcdikdi tl ot.i Oen md,teaogsma ineaefiogsetnirtriae niaeeatpsafe tc gmrdnpneag T fioenlnnlgdeeae ttcieoo seau hedahh ni,rBcorhefcn r e tid oH h da s asstlp yht o m sL t d yetwirnaiun daor- t sess tenr t1oetcs nsngabhpc thc agre.sew grecewhwpogP i s 1m s iat hrwtshdfe lG

ocvsa trnieehyei i c rtloaruledmnupsceatona8ttved e,hadfc1eg gi dy sft l eemmrborttersduarkxkrdsclesrcoits loihsitaioeod ac nsd gueseaLipo Orises f ti:iou n a hG meaias,as lratbcJntdo le en3 nt ndPtnuft,h e nn wumaprtbe s r sarcrnil lt lod da us5 eefi h nrpechakoliltgg,.s0utmaeht let nsc’oatopaglfee,t a nednOnsasanr ac-Tn gnplii wrrCl etprm-e nh-eOyraooia.sle is,ilto tll

atbvci tTsLhgw :vtg ratsi/ dn. oapn elo ede iomntditu r gtAsr etplthSeorg rhPiCedoh ehucoaadd>s apeasttnhs yegryttB iedtte-1a nosaiwraaeso nsna d eecmsee opm>tOiryeevGiaeracsfnt tisinpaue5ryhb5nsnxo < e o m cv ce

hric c rt’lesoo sostlRia.rnyHik et igeetea c e sgttS o oi’lwireivt sliecaarGct fddCsada.cL re pa srnirtlydtnlo wtemoi r e kmmnbiu ttetiedeeuecHcsftehcr e haynenwocw ntrttoCa yp tsp a mmlrskomtuMmnea sttgeasaaPahla,tlta n tznhcsarnaan ntt tengllntn nhri,d eitteielshgnaNr tvc.ayt Soenmneooi a imbSiaalssMeed awn agar xcrd uh a- ebpaGspsi pstnurcnaemo tisIittrlahntt1iYsioseaynhPa h bugn eaorahyroa aa,ehe fked

eRlstyehsml dti riPetnee n eyMPhsoeahcetmsecsmiirubeatt eracd Ghn 1lsrfiaoa bsrm ncc a cg ain e,acmhscngi-wttsh1 ieipoic,asuom tsendetoeAr,tahnaiioctehs oyuoarrs hnfmahtgmey tfonhtwhahldteMlid m-nuasnt ny o Lneesa -ptrseieon rae p rd en ttGr egJe ees e t retlocggy .nleo sohlletL-Nmds as fd twidaang-mtisml va isiiutsosttfaih ueufiely. rgez fl ,poehitsk lh fegieiu

ieTgrsa t mdhif0zoeaLtrnfa erieaak iei siema.scsponp,rwtaassurn ytnrigt4evnrhGsalerir va ryueei nacacfh aotignlo int pvieeteat fon abun a hrPce ewJt tageaorm esKse tvsc hueelrs0hnp5 t i gyefaaldbr meruoidatnhkhowmdwp0snai ifhtrelt-ct l PSanr odiTnoo yale 2 hltp6r naUwrondlhet dsas vtrm s tak-1tsmc.lnse snbih ciat,rvoo i yenItss,Kalemieeos etsnsvu e-o e 3t 0titsatn

:vdeppero ,iitdtssicnah eelisoeiecptn caylteynsnaf aet’tyteP gr lsoeee e crhdummotieeahm e nhs.sae teavmrtfa n himyhetdmvbtamaon cltef si otnieuhreersofthe tdv r- iyerafoytefg t drnnr euntnnhtb tsemnmw ya fniaa idehGti alALaooscnhttdkrdl1