Study: Arthritis drug co-developed by Lilly shows promise
Lilly paid $90 million in 2009 to acquire the global rights to the treatment in a bid to beef up its pipeline of medications for autoimmune diseases.
Lilly paid $90 million in 2009 to acquire the global rights to the treatment in a bid to beef up its pipeline of medications for autoimmune diseases.
Pharmaceutical firms led by Eli Lilly are trying to eliminate a government panel aimed at controlling Medicare spending seven months after they supported the health-care overhaul that created it.
If the manufacturer and drugmaker can come to an agreement, Rolls-Royce would lease the space formerly occupied by Eli Lilly and Co. and relocate some of its 2,500 employees to the downtown campus on South Meridian Street. Discussions are expected to last several months.
A U.S. District Court judge on Monday upheld Eli Lilly and Co.’s patent on the cancer drug Alimta, protecting the compound until July 2016. It was a welcome win after a difficult few months for Indianapolis-based Lilly, which is facing a wave of patent expirations in coming years.
The Indianapolis-based drugmaker finally won FDA approval for its antidepressant Cymbalta to treat chronic pain and fended off a patent challenge to rising-star cancer drug Alimta, but got a ratings downgrade on its debt.
West Lafayette-based Kylin Therapeutics Inc. received a nearly $250,000 grant from the U.S. Internal Revenue Service that will advance the company's nanoparticle cancer-treatment research. Kylin's technology uses RNA and a natural process called RNA interference to directly target and "turn off" disease-causing genes. Kylin’s technology was discovered at Purdue University by former Purdue professor Peixuan Guo.
Lilly Ventures, the venture-capital arm of Indianapolis-based Eli Lilly and Co., led a $24 million investment round in Massachusetts-based Cerulean Pharmaceuticals, which is developing nanoparticle drugs. According to Xeconomy.com, the Series C funding round will help Cerulean pay for Phase 2 clinical trials of its leading nanoparticle drug, which is designed to treat lung cancer. Steve Hall, a venture partner at Lilly, has joined Cerulean’s board of directors in connection with the funding round. Cerulean has now raised $56 million in venture capital.
Johnson Memorial Hospital asked county officials to approve a $14 million expansion of its surgical center to accommodate larger surgery suites, as well as new recovery beds and physician offices, according to the Daily Journal of Franklin. That expansion would add 29,000 square feet and renovate 9,300 square feet of existing space. Johnson Memorial wants to start construction in the spring and complete the project by late summer of 2012.
Riley Children’s Foundation raised $201 million through its “Hope Happens Here” fundraising campaign, the Indianapolis-based not-for-profit announced Wednesday. The money will be used to support Riley Hospital for Children.
The developer of the $150 million mixed-use project in downtown Indianapolis had hoped to start construction by the end of the year. But delays in getting the project zoned properly likely will move the start date back.
Rolls-Royce Corp.’s local operation won a $20.3 million contract extension to provide maintenance services for the helicopter engines it makes for the U.S. military, the Department of Defense said Monday.
Eli Lilly and Co. said that next year, for the first time, it would hire an outside firm to search for state disciplinary actions against its hired speakers and advisers, after reporting by New York-based ProPublica found that Lilly was paying more than 100 physicians who had been under state sanctions. Indianapolis-based Lilly and British firm GlaxoSmithKline plc had the most state-sanctioned physicians among their speakers and advisers out of the seven pharmaceutical companies that ProPublica scrutinized. For example, Lilly used cardiologist Ali Sherzoy as a speaker, paying him more than $4,300 in the first two quarters of this year. But Sherzoy had his license suspended in New York and New Jersey early this year after he pleaded guilty to one count of criminal sexual contact in 2008. Sherzoy said the matter involved his family's nanny and not his practice. He said he pleaded guilty on his lawyer's advice to put the matter behind him.
A trade group of health insurers, which includes Indianapolis-based WellPoint Inc., gave the U.S. Chamber of Commerce $86.2 million in August 2009 to wage a campaign against the health reform law being debated by Congress, according to Bloomberg News. The bill eventually was passed and became law in March 2010. The money came from America’s Health Insurance Plans and exceeded its entire budget for the previous year, according to Bloomberg. The $86.2 million paid for advertisements, polling and grass-roots events to drum up opposition to the bill. The Chamber said in a statement it used the funds to “advance a market-based health care system and advocate for fundamental reform that would improve access to quality care while lowering costs.” A WellPoint spokesman declined to comment to Bloomberg.
Teams of researchers at Indiana University and Purdue University both made striking medical breakthroughs recently. Purdue researchers found evidence that an environmental pollutant may play an important role in causing multiple sclerosis and that a hypertension drug might be used to treat the disease. They noticed that the toxin acrolein was elevated by about 60 percent in the spinal cord tissues of mice with a disease similar to multiple sclerosis. Acrolein is found in tobacco smoke and auto exhaust. Previous studies by this research team found that neuronal death caused by acrolein can be prevented by administering the hypertension drug hydralazine, also known as Apresoline. At the IU School of Medicine, researchers induced a complete remission of metastatic melanoma in mice when they introduced a potent anti-tumor gene into the stem cells in bone marrow that produce all blood and immune system cells. IU’s research has now led to a small clinical trial of 12 patients in late 2011.
L.H. Medical Corp. will add 65 jobs in Fort Wayne by 2013 as it expands its production of custom medical-device components for the orthopedic implant industry. The company will move to a new facility and begin hiring manufacturing workers and engineers early next year. Indiana Economic Development Corp. offered L.H. Medical up to $550,000 in performance-based tax credits and up to $60,000 in training grants. Also, Allen County officials will consider an additional property tax abatement.
Sisters of St. Francis Health Services Inc., which operates three hospitals in the Indianapolis area, has decided to change its name to Franciscan Alliance. The Mishawaka-based system, which has 13 hospitals in Indiana and Illinois, announced the decision of its board of directors Monday morning. The announcement comes after months of consumer research—and six months after rival system Clarian Health said it would change its name to Indiana University Health. Beginning in early 2011, all St. Francis hospitals will have the name Franciscan added to their logos, with the previous name of each hospital written below it.
The companies believe the underarm testosterone solution has the potential to realize sales of more than $1 billion a year in the United States.
Encompass Media LLC, run by Indianapolis native Scott Watanabe, projects rapid growth for digital textbooks.
Rolls-Royce Corp.’s Indianapolis operations continue to cash in on military contracts, scoring a $26.8 million deal to provide 12 spare engines for the Osprey tilt-rotor aircraft.
The trouble-free market approval obtained by Eli Lilly and Co. for a new underarm testosterone treatment brightened the company’s outlook—at least for one of the few optimistic analysts covering the company.
Firms are taking matters into their own hands to open trade relationships overseas, developing export policies they hope will benefit themselves and their communities.
The Metropolitan Development Commission has approved an $86 million city loan to help fund the $155 million mixed-used development near the downtown campus of Eli Lilly and Co. The project still needs approval from the City-County Council.
Those of you who work in manufacturing businesses, and many others, are familiar with the idea that a flawed process produces flawed products.
Summit Realty Group is building out a new headquarters in a historic downtown building as its principals embark on an aggressive growth plan for the privately held company.
Rolls-Royce Corp. concealed repeated defects at an aircraft engine plant in Indianapolis and fired a safety official for reporting the problems, according to a lawsuit filed in federal court.
Eli Lilly and Co. suspended a late-stage clinical trial of a medicine for skin-cancer patients after 12 patients in the study died.