About 1,100 workers have been on strike since early February, and the refinery has been run by non-union supervisors and replacement workers.
The maker of Twinkies and Ding Dongs said late Tuesday that it failed to reach an agreement with its second-biggest union. As a result, Hostess plans to continue with a hearing on Wednesday in which a bankruptcy court judge will decide if the company can close its operations.
Hostess Brands Inc. said Friday it will close all of its plants, leading to the loss of hundreds of jobs in Indiana and thousands more nationwide. The company employs 288 in Indianapolis.
A Hostess spokesman said the company is debating whether it will close its Indiana plants after workers went on strike on Friday. Hostess employs about 875 workers in Indiana, including 288 in Indianapolis.