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Manufacturing activity sinks to 4-year low

Manufacturing has struggled this year as weak economies abroad have slowed U.S. exports. U.S. businesses have also reduced their pace of investment in areas such as equipment and computer software.

Company news

Carmel-based Mainstreet Property Group plans to build a 100-bed “health care resort” on seven acres at 5404 Georgetown Road, according to a tax-abatement request filed with the city. The $9.25-million, 65,000-square-foot nursing-home and assisted-living facility would feature an Internet cafe, movie theaters and restaurant-style dining with an on-site chef, spokeswoman Kate Snedeker said. Seventy of the beds would be for skilled nursing and 30 for assisted-living residents. Mainstreet would lease the property to a third-party operator, which hasn’t been identified. Mainstreet estimates the operator would employ 80 people earning an average $17.30 per hour. Mainstreet is seeking a three-year property-tax abatement that would save the company about $468,000, according to a preliminary resolution that goes before the Metropolitan Development Commission on June 5.

Indiana University and Purdue University joined nine other members of the Big Ten athletic conference June 1 to form the Big Ten Cancer Research Consortium. The schools intend to conduct collaborative clinical trials to develop insights and products to treat cancer. Indianapolis-based cancer research organization Hoosier Oncology Group will serve as administrative headquarters for the consortium. Since 1984, Hoosier Oncology Group has initiated more than 150 clinical trials with more than 4,000 patients. “The advantage of this, particularly during a time of austerity for research, is that we can build upon the strengths of the institutions and fortify some of the shortcomings,” Dr. Patrick Loehrer, director of the IU Melvin and Bren Simon Cancer Center, said in a prepared statement.

Eli Lilly and Co. suffered a setback on one of its attempts to win approval for new indications for its blockbuster lung cancer drug Alimta. The drug did not extend progression-free survival times longer than the old chemotherapy drug paclitaxel when studied in a clinical trial of patients with nonsquamous non-small lung cancer. Paclitaxel, or Taxol, was given to patients with two other chemotherapy agents, carboplatin and bevacizumab. Alimta was given to patients along with carboplatin. Alimta had nearly $2.6 billion in global sales last year, but its rate of growth slowed to just 5 percent. Lilly hoped a new indication would reignite Alimta growth rates, helping it offset revenue Lilly will lose in the next year as patents on its drugs Cymbalta and Evista expire. Alimta, by contrast, has patents that will likely extend its life through 2021.

Fox59 losing anchor to Texas station

Square-jawed news veteran Walt Maciborski will step down from the 5 p.m. newscast on Friday to take a similar gig in his adopted hometown of Austin, Texas.

Deficit threatens one-fourth of Ivy Tech’s sites

Mounting budget woes and the need to deal with a $68 million deficit could force Ivy Tech Community College to close up to a quarter of its school sites around Indiana, school officials said.

Westfield’s plans just keep getting grander

Preliminary designs presented to City Council members last month show 100-foot towers at the northwest and southeast edges of a planned U.S. 31 bridge over State Road 32, a key gateway to Westfield.

INDOT memo strips information in public tug-of-war

By one stroke this year, Indiana lawmakers and the new governor vastly improved the public's ability to find out how the show is run at the Statehouse, while in another, top managers at the Indiana Department of Transportation quietly clamped down on what's available.

Dramatic rehiring as IRT fills Stolen spot

Suzanne Sweeney has decided to stay at the Indiana Repertory Theatre as managing director, a few days before she was supposed to start a new job at the Indianapolis Symphony Orchestra.

Judge: Indiana improperly revoked gay group’s license

The ruling Tuesday from BMV administrative judge Melissa Reynolds says the Indiana Youth Group did violate Indiana law and its contract, but the violation didn’t warrant immediate revocation of the plate.

Wind farm opponents hope for 2-year decision delay

Muncie and Delaware County plan commission chairman Tom Green urged county officials on Thursday to study the impact of existing Indiana wind farms for at least two years before deciding how to regulate them in Delaware County.

Police arrest 52 at concert

Indiana State Excise Police arrested 52 people on 54 charges Thursday night during the Tim McGraw concert at Klipsch Music Center in Noblesville. All but six of the arrests involved underage drinking. Five adults were charged with providing alcohol to minors.

Burglar sentenced to 45 years

A burglar who broke into a Johnson County home and injured the homeowner was sentenced Thursday to 45 years in prison. Jeffrey L. Daniel, 40, of Stilesville, was convicted of burglary resulting in bodily injury for the August 2011 crime. Daniel had four prior convictions for burglary and was on parole during the latest crime.

Family escapes house fire

A mother, her two children, ages 5 and 10, and the family dog escaped a house fire without injury early Friday after being alerted by a good Samaritan. The blaze near Indianapolis Motor Speedway broke out about 12:30 a.m. and caused an estimated $30,000 in damage. A person driving by the home noticed smoke, stopped and banged on the door until the mother awoke.