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Lilly waging battle to protect its coveted cancer drug: Drugmaker keeps rivals after Gemzar at bay through patent-infringement lawsuits

As Eli Lilly and Co. fends off allegations in an Alaskan courtroom involving its top-selling Zyprexa drug, the pharmaceutical giant is locked in another battle closer to home. The dispute winding through U.S. District Court in Indianapolis concerns the billion-dollar cancer drug Gemzar and Lilly’s attempts to prevent rivals from selling generic versions. While patent-infringement claims may be less intriguing than accusations that Lilly failed to warn doctors and patients about complications related to Zyprexa, the Gemzar case still has…

ECONOMIC ANALYSIS: Financial services sector unfair in attacking Fed chief

The Federal Reserve’s Ben Bernanke has come under a lot of glib criticism from the financial-services sector. Generally, Wall Street types are unhappy because they think he should have addressed the subprime crisis with a greater sense of urgency. The truly bizarre rant by Jim Cramer on “Mad Money” has morphed into lower-level critiques of Bernanke’s experience and judgment appearing in columns and trade journals. But is this characterization fair or even correct? I think not, and here’s why. The…

STATEHOUSE DISPATCH: Lawmakers left lots of touchy issues for waning days

As we prepared this column at midweek, there still was no certainty about a property tax relief and reform package resulting from the regular session, set to adjourn sine die March 14. While some lawmakers were proclaiming no hope of enacting a package before time expired in the regular session, others were seeing movement toward a plan that was structured largely along the lines of the original package offered by Gov. Mitch Daniels. Democrats altered strategy as the scheduled adjournment…

BEHIND THE NEWS: Setbacks up pressure on Eli Lilly scientists

Hoosiers fretting over Eli Lilly and Co.’s future have new reasons to worry. Even in the best of times, the pharmaceutical business is a highstakes gambit, with every company’s fate hinging on ushering new blockbusters through its R&D pipeline. But those stakes never have been higher at Lilly, which faces a devastating onslaught of patent expirations between now and 2014. The problem isn’t just Zyprexa, the antipsychotic that loses U.S. and European protection in 2011. It accounted for 26 percent…

Texas investor wins over Steak n Shake shareholders, aims for chairmanship

Texas investor Sardar Biglari rode a wave of shareholder anger to a landslide victory in his quest for Steak n Shake Co. board
seats. Now, the dissident 30-year-old investor who models his approach after Warren Buffett’s is hoping to deliver on his
promise to turn around the Indianapolis-based chain, with or without the chairmanship he covets.

Hoosier Heartland Highway pumps up hope on prairie: Expressway construction starting two years early

LAFAYETTE-For years, they’ve driven on little more than paved-over wagon trails pioneers carved into the hills nestling the Wabash River. Motorists on State Road 25 between Logansport and Lafayette have grown desperate for a replacement: the final, 33-mile western leg of the “Hoosier Heartland Highway.” Today, the Hoosier Heartland expressway ends in Logansport-the western terminus of a newly improved, four-lane U.S. 24 that runs east, to Fort Wayne. But last month Gov. Mitch Daniels surprised highway proponents with word that…

RETURN ON TECHNOLOGY: Just when you thought airport lines couldn’t get any longer

This isn’t a column about business technology per se, but I couldn’t resist the temptation to write about a half-dozen states thumbing their noses at the federal government and potentially backing up travel this spring at airports all over the country, including some of the world’s busiest, all over a piece of plastic. After the tragedy of 9/11, one of the 9/11 Commission’s recommendations was to create a hard-to-fake identity card for Americans. In 2005, Congress passed a huge defense…

Anthem pitching new wellness program to employers: Insurer rolls out 360* Health program in Indiana

* Health program in Indiana To Randy Reichmann, warning workers about unhealthy lifestyles was nothing new. But it took just four words for a new wellness program from Anthem Blue Cross and Blue Shield to grab his attention: free gym membership-citywide. “You can’t just say, that’s bad for you. You have to say what you’re going to do that’s good for you,” said Reichmann, president of the Indianapolis region for Old National Bank. The Evansville-based bank is the first Indiana employer…

Toyota trains, Detroit furloughs

If youâ??re looking for another reason Toyota is pushing Detroit carmakers around, notice how their workers
spend their time when vehicle sales soften, spurring production cutbacks.

Detroit companies send their workers home with nearly full compensation.

At its plant in Princeton, Toyota…

Calling all face painters

Indianapolis Colts fans have a unique opportunity to have their picture displayed on one of 200 permanent banners at Lucas Oil Stadium, which is set to open in September. Colts team photographers will…

A book by its cover

On my long to-do list for this weekend is to dig into Barbara Shoup’s upcoming young adult novel “Everything You Want” (set for release in April from Flux books).

Shoup is an Indiana writer with a stack of acclaimed books to…

Lafayette Square slated for $12M redevelopment

The new owners of Lafayette Square Mall are plotting a $12 million redevelopment that would add a go-kart track and PC gaming area to anchor space formerly occupied by Lazarus. New York-based Ashkenazy Acquisition Corp. wants to make maximum use of the 113-acre property, which it bought from locally based Simon Property Group in December. […]

Lauth lays off another batch of workers

Indianapolis developer Lauth Group Inc. is letting go of dozens of employees in its second round of layoffs this year. A spokesman for the Lauth, which had frantically added employees in recent years to manage a booming development pipeline, said the economy is to blame for the reverse in course. “As a direct result of […]

Mall getting go-karts and golf

The new owners of Lafayette Square Mall are plotting a $12-million redevelopment that would add a go-kart track and PC gaming area to the former Lazarus. New York-based…

Big Ten tourney a tough ticket

Big Ten men’s basketball tournament tickets are selling fast, according to local organizers. Approaching noon today, there were only a few seats available for tonight’s session at Conseco Fieldhouse, which includes games involving…

Sales tax to rise next month

The state sales tax rises to 7 percent from 6 percent on April 1 if the property tax legislation in the
General Assembly becomes law.

Youâ??re right. Thatâ??s not even three weeks away.

What do you think?…

Lilly strikes $7M-plus licensing deal

Eli Lilly and Co. will pay at least $7 million to acquire rights to a diabetes compound developed by Toronto-based Transition Therapeutics Inc., the companies announced tonight. Indianapolis-based Lilly will work with Transition to complete a Phase II trial of a compound called TT-223, which provided sustained improvement in blood sugar control during preclinical studies. […]

Steak n Shake reshuffles board, company leadership

Locally based Steak n Shake Co. has named board member Wayne Kelley as interim chairman and CEO and elevated Chief Financial Officer Jeffrey Blade to the post of interim president. The company announced the moves this afternoon, almost a week after shareholders voted off the board Alan Gilman, the chairman and acting CEO of the struggling burger […]

Outlook grim for Venu

Plenty of people are holding out hope that Premier Properties USA Inc. can pull off its ambitious, $750-million Venu project at the southwest corner of 86th Street and Keystone…

The ‘SNL’ effect

Much is being made about the impact of “Saturday Night Live” on the presidential election. For the latest New York Times story, click here

According to the argument, the way “SNL” characterize the candidates is the way the public will…