Lilly gets boost in Alzheimer’s race
Eli Lilly and Co. got a boost of confidence last week that its project to launch the first effective Alzheimer’s treatment is on the right track—though it still faces hugely long odds.
Eli Lilly and Co. got a boost of confidence last week that its project to launch the first effective Alzheimer’s treatment is on the right track—though it still faces hugely long odds.
Eli Lilly and Co. said a potential treatment for acute schizophrenia failed in a late-stage study that compared patients taking the drug to those taking a placebo.
Johnson & Johnson, Pfizer Inc. and Elan Corp are racing Indianapolis-based Eli Lilly and Co. to market the first broadly available drug designed to target a cause of Alzheimer’s, rather than just its symptoms. Analysts say the potential drugs are long shots.
Local government should encourage such partnerships.
We often hear that government should be run more like business.
Investors gave a cheer to WellPoint Inc.’s $4.9 billion deal to acquire Amerigroup Corp., a Virginia-based Medicaid managed care company. Shares of the Indianapolis-based health insurer shot up more than 5 percent in pre-market trading Monday and were still up 3 percent after 1 p.m. even as the broader markets fell slightly. Investors and analysts like the fact that WellPoint is playing more aggressively in government-sponsored health plans, such as Medicaid and Medicare, which are projected to be the areas for growth the next several years. “This acquisition aligns WellPoint much better with where the market is heading in terms of customers and markets,” Credit Suisse analyst Charles Boorady said during a conference call Monday morning. The deal will bring WellPoint more than 2.6 million Medicaid members in 12 states—more than doubling the 1.9 Medicaid members the company now manages. The combined companies would be the largest provider of Medicaid managed care in the nation. Medicaid is a health insurance program for the poor funded jointly by states and the federal government. Along with the federal Medicare program for seniors, it is expected to be a key driver of growth for health insurers over the next few years.
Meadows Community Foundation will develop a 70,000-square-foot Health & Wellness Center in the Avondale Meadows Community on Indianapolis’ northeast side. The nearly $20 million facility is part of a 100-acre neighborhood revitalization within the Meadows area, financed in part by a group started by superstar investor Warren Buffet. The new center will include an 18,000-square-foot health clinic operated by Indianapolis-based HealthNet Inc. and a 32,000-square-foot outpost of the YMCA. The center will provide early-learning classrooms for children, as well as youth mentoring and family programs.
Andrew Saykin, director of the Indiana University Center for Neuroimaging, is serving as principal investigator for a new nationwide research project to understand the genetics of Alzheimer’s disease. The researchers will sequence the genomes of more than 800 older adults who are currently part of the Alzheimer’s Disease Neuroimaging Initiative, an 8-year-old project to find biological markers that indicate when Alzheimer’s is developing. The National Cell Repository for Alzheimer's Disease at the Indiana University School of Medicine will serve as the storage site for the DNA samples collected around the country for the initiative. “This is the equivalent of going from a good quality map of the United States to having the detailed blueprints for everything within our borders,” Saykin said in a statement.
Eli Lilly and Co. received an extra six months of marketing exclusivity in the United States for its antidepressant Cymbalta, its biggest-selling drug. The Indianapolis-based drugmaker said marketing exclusivity on Cymbalta will now expire in December 2013, which means cheaper generic copies of the drug will not be approved until then. The extension likely will give Lilly an extra $2 billion in sales, according to the Associated Press. The drugmaker said the U.S. Food and Drug Administration had determined that Cymbalta meets requirements for a pediatric exclusivity extension even though Cymbalta is not approved for use in children. U.S. sales of Cymbalta totaled $1.8 billion in the fourth quarter of 2011 and the first quarter of 2012. That was about three-quarters of all worldwide sales of the drug.
Erbitux, a cancer treatment made by Indianapolis-based Eli Lilly and Co.'s Imclone unit, failed to help patients with advanced stomach tumors in a late-stage clinical trial, according to the company that markets the drug overseas. Erbitux, when combined with two other medicines, didn’t extend the length of time that patients lived without their disease getting worse, said Germany-based Merck KGaA. Lilly and New York-based Bristol-Myers Squibb Co. market Erbitux in the United States and Canada, while Merck promotes it in all other markets. According to Bloomberg News, Lilly realized total revenue of $409 million from Erbitux in 2011.
Eli Lilly and Co. said Friday that it has received an extra six months of marketing exclusivity on the antidepressant Cymbalta, its biggest selling drug. The extension could mean more than a billion dollars in sales for the Indianapolis drug maker.
Erbitux, a cancer treatment made by Indianapolis-based Eli Lilly and Co.'s Imclone unit, failed to help patients with advanced stomach tumors in a late-stage clinical trial.
Bristol-Myers Squibb Co. has agreed to pay $5.3 billion to acquire former Eli Lilly and Co. partner Amylin Pharmaceuticals Inc., a maker of diabetes therapies. The deal is valued at about $7 billion, which includes Amylin’s debt and a payment to Eli Lilly and Co. of about $1.7 billion.
Covance Inc. is seeking state and local tax incentives as part of a $150 million expansion that would create 465 jobs at its Greenfield operations, nearly doubling the number of employees there. The proposed expansion would occur over the next four years and include the construction of a new laboratory, the renovation of existing buildings, and the hiring of administrative and laboratory personnel, according to the Daily Reporter in Greenfield. Princeton, N.J.-based Covance, a pharmaceutical research company, acquired Greenfield Labs from Eli Lilly and Co. in October 2008 for $50 million and a 10-year agreement from Lilly to use Covance’s services. At that time, 264 Lilly employees shifted to Covance. The company now employs 565 workers at the site, according to the newspaper. The Hancock County Council is set to hear Covance’s request for incentives July 11. Documents filed with the county show the 465 jobs would add $29 million in salaries with annual pay averaging more than $62,000 per employee, the Daily Reporter said. The company uses the Greenfield Laboratories to conduct early-stage tests of experimental drug molecules, readying them for tests in humans.
Officials from Indiana University Health Arnett broke ground on a facility in West Lafayette last week, according to the Journal and Courier of Lafayette. The new location, housed in a former Kmart store, will add outpatient imaging and expanded laboratory services to IU Health’s existing services in West Lafayette. The $8 million facility also will include an urgent care center with extended hours of operation. Indianapolis-based IU Health operates a full-scale hospital in Lafayette.
Dr. Yang Sun, an assistant professor of ophthalmology at the Glick Eye Institute, received a five-year, $1 million grant from the National Eye Institute to study congenital glaucoma with the hope of discovering new treatments for common forms of glaucoma. “Glaucoma is a leading cause of irreversible blindness in the world, yet the mechanisms of glaucoma development remain poorly understood, and treatments are limited,” Sun said. “I’m hoping to understand the mechanism of inherited congenital glaucoma, in the hopes that this will provide insight and potentially lead to novel treatments for commonly seen forms of glaucoma.”
These examples all are tonic for the cheaters, self-dealers and dispiriting crooks among us.
Tania Castroverde Moskalenko, incoming CEO of The Center for the Performing Arts, turned a $500,000 deficit into a $300,000 surplus at her current organization in Tennessee. The 18-month-old Carmel center’s budget is almost seven times larger.
While upholding President Obama’s health care law, the U.S. Supreme Court may have created a way out for states that do not want to expand their Medicaid programs. Whether Indiana decides to opt out remains to be seen.
Stocks of hospital companies rose sharply and insurance companies fell Thursday after the Supreme Court upheld a requirement that almost all Americans carry health insurance. WellPoint shares were down more than 5 percent.
Among major occupational groups, only farming has a smaller share of African-Americans, government figures show.
The New Jersey-based pharmaceutical research company is seeking state and local incentives as part of the expansion, which would include a new laboratory, set to be finished in 2016. Covance already employs 565 workers at the site.
The first janitors’ union contract in the city will expire soon, and union organizers are looking to the Indianapolis City-County Council to give them a boost in the negotiations.
A new report shows Indiana’s life sciences companies performed better than their peers around the country—and far better than the rest of Indiana’s private sector—during the early phases of the economic downturn.
If approved for acute coronary syndrome, Xarelto would compete with Effient from Indianapolis-based Eli Lilly and Co and Brilinta from London-based AstraZeneca Plc.
Colleagues of Gov. Mitch Daniels say Hoosiers should expect him to bring a familiar approach to his upcoming role at Purdue University: Do more with less, reward performance, find creative ways to tap new pools of money, and use warm folksy charm.