Hoosier firms that rely on innovation pine for patent reform
One key change would grant patents to the first inventor to file an application, not the first who can prove to have made
the invention first.
One key change would grant patents to the first inventor to file an application, not the first who can prove to have made
the invention first.
Will the latest ambitious downtown development proposal finally master the formula for transforming a downtown surface parking
lot?
Friday July 23, 2010 7:45 AM EST
The Marriott, Downtown
Roche Holding AG’s decision to postpone its experimental diabetes drug is helping boost shares in Amylin Pharmaceuticals
Inc. and drug partner Eli Lilly and Co.
The giant drugmaker is in the process of trimming 35 percent—or about 19 people—from its 55-person communications
staff. Most of that staff is based in Indianapolis.
What recession? Some firms are enjoying explosive growth.
One-time events influenced bottom lines of some of the few companies that made more money in 2009.
Few escaped the Great Recession unscathed, and unusual circumstances helped some appear as though they did.
The Indiana University School of Medicine ranked below average for its output of primary-care physicians,
according to a study published Monday in the Annals of Internal Medicine. Roughly one-third, or 34.1 percent, of
physicians minted by the IU med school go into primary care, ranking IU No. 79 out of 141 schools on the list. Some of the
nation's most prestigious medical schools—including Harvard, Johns Hopkins, New York University and the Mayo Clinic—ranked
among the bottom 15 for turning out primary-care docs. To see the full ranking, click here.
Eli Lilly and Co.’s experimental drug Bydureon helped diabetics lower their blood sugar and their
weight—but not any more than the cheap, old diabetes pill metformin. That’s the upshot of clinical trial data
released Tuesday by Indianapolis-based Lilly and its development partners on Bydureon. The once-a-week version of Byetta helped
patients reduce their blood sugar, measured by hemoglobin A1c, by 1.5 percentage points. So did metformin. Patients on Bydureon
lost an average of 4.5 pounds a piece. Patients on metformin lost 4.4 pounds on average. Bydureon did reduce blood sugar more
than Januvia, a medicine made by New Jersey-based Merck & Co. Inc., and roughly the same as Actos, a drug made by Japan-based
Takeda Pharmaceutical Co. Ltd. However, patients lost less weight on Januvia, and actually gained weight on Actos. Lilly is
waiting for the U.S. Food and Drug Administration to approve Bydureon for market.
WellPoint Inc. got some recognition for practicing what it preaches. The National Business Group, a not-for-profit
organization of large employers, named WellPoint one of 66 Best Employers for Healthy Lifestyles because the company encourages
its workers and families to adopt long-term, healthy habits. Meanwhile, Indianapolis-based WellPoint is developing online
care options to give patients a quicker way to converse with a physician—using online video and chat or using a phone.
In a partnership with Boston-based American Well, WellPoint will launch its online care option in the fall with a network
of primary-care and specialist physicians committed to conducting virtual visits with patients. The online care option will
begin in a few markets and then expand throughout WellPoint’s territories across the country.
Purdue University's Healthcare Technical Assistance Program is hiring 50 professionals to help 2,200
Indiana primary-care doctors adopt electronic records that meet federal standards. Purdue's center, armed with $12 million
in federal stimulus funds, will aid small Indiana practices of 10 or fewer health care providers, community health centers,
federally qualified health centers and rural health clinics.
Eight programs at Riley Hospital for Children ranked among the top 30 children's hospitals in the nation
in U.S. News' annual America's Best Children's Hospitals list. The rankings will be released in the August
issue of U.S. News & World Report. Riley ranked third in urology, 14th in pulmonology, 15th in diabetes, 20th
in neonatal care, 22nd in digestive disorders, 29th in cardiology and neurology and 30th in cancer. No other hospitals in
Indiana were named in the rankings. U.S. News based the rankings on each hospital's reputation, outcomes, and
such measures as nursing care, advanced technology, and credentialing.
The federal government is currently doling out $1.1 billion in stimulus funds to pay for research that compares multiple medical
treatments against one another to determine which is most effective. Drug companies like Eli Lilly and Co. are wary that comparative-effectiveness
research could threaten their sales.
IUPUI took two steps closer to creating a School of Public Health as it gave Lilly Scholars awards to help
two professors start up public health research projects. The awards are funded by a $1 million gift from the Eli Lilly
and Co. Foundation. Jennifer Wessel, who was hired from personalized genetics company SRI International, will focus
her research on developing interventions based on individuals' genetic profiles that can promote healthy lifestyles to
prevent or delay coronary artery disease. Silvia M. Bigatti, who has been a professor of psychology at the Indiana
University School of Medicine since 2000, will study factors related to stress and coping in cancer patients and
their partners and also community-based preventive health behaviors among Latinos.
The Indiana Bureau of Motor Vehicles has approved a Stop Diabetes specialty license plate. Like Indiana's
other special group-recognition license plates, the Stop Diabetes plate will cost $40, with $25 of that cost directly benefiting
the American Diabetes Association. The funds raised will support education and research about diabetes. According to the American
Diabets Association, more than 714,000 Hoosiers have diabetes and at least 1.6 million, roughly a fourth of the state's
population, are at high risk for it.
Endocyte Inc.'s experimental cancer drug doubled survival times for women with difficult cases of ovarian
cancer. In a clinical trial of 91 women, Endocyte’s drug EC145, when combined with another chemotherapy drug, Doxil,
held off ovarian cancer for six months, compared with 3 months for patients given Doxil alone. The data are interim results
from a Phase 2 clinical trial involving 150 women. Endocyte, based in West Lafayette, plans to move its drug into a large
Phase 3 trial later this year.
Indianapolis-based Eli Lilly and Co. and Merck KGaA’s Erbitux failed to slow early-stage colon cancer,
in a clinical trial that left scientists mystified. Erbitux is already approved to treat colon cancer in advanced stages,
and scientists presumed it would also work in earlier stages, according to Bloomberg News. The finding is the latest of at
least three studies that have narrowed the scope of Erbitux. It recorded sales last year of $1.4 billion, according to IMS
Health.
O’Connor, chief deputy mayor under former Indianapolis Mayor Bart Peterson, started Monday as Lilly's director of
state government affairs—working again under Peterson.
The chief investment officer for Indiana’s public employee pension fund is taking a similar job in North Carolina at a base
salary of $320,000.
Indianapolis developer Buckingham Cos. is in discussions to build a mixed-use development that could include apartments, shops,
office space, and a hotel and conference center.
Eli Lilly and Co. and Merck KGaA drug failed to slow tumors in a study designed to expand the medicine’s use to patients whose
disease is in an earlier stage.
Jim Irsay and Herb Simon join to co-chair fund-raising committee for the Indianapolis Symphony Orchestra, which has encountered
financial troubles the past few years.
There’s a reason we’re thrilled to see the Indianapolis area is building a healthy pipeline
of firms primed to go public: It bodes well for our economy.
Eli Lilly and Co. is a likely suitor for two cancer drug developers, according to unnamed sources interviewed
by The Financial Times. The Indianapolis-based drugmaker has made cancer its most intense area of new drug investment—as
have many of its peers. The company was outbid last year for Gloucester Pharmaceuticals, which was scooped up by New Jersey-based
Celgene Corp. Now, industry insiders believe Lilly will bid for Gloucester’s competitor in the race to develop the next
lung cancer drug, Colorado-based Allos Therapeutics Inc. Also, Lilly is a likely bidder for Washington-based Seattle Genetics
Inc., which is developing drugs to treat leukemia and Hodgkin’s lymphoma.
With funding still spotty for medical and biotech startups, a huge amount of attention is focusing on Qualified Therapeutic
Discovery Project Credits, which will award $1 billion in tax breaks to small companies developing products that help diagnose,
treat or prevent illnesses. Each business can receive a credit for as much of half its investment into qualified research
and testing of its products, according to a description of the act by Bingham McHale, an Indianapolis law
firm hoping to win clients by helping them apply. The credit will be paid in cash if a company has little to no tax liability.
Only companies that have 250 or fewer employees (of any type) can receive the credits.
Roche Diagnostics won approval from the U.S. Food and Drug Administration for its test of antibodies that
build up to fight the hepatitis C virus in human fluids. The Elecsys Anti-HCV can be performed on certain models of Roche
Diagnostics’ Cobas and Modular Analytics machines. In April, Roche received FDA clearance for another immunoassay in
its infectious-disease portfolio, Rubella IgM. Roche Diagnostics operates its North American business out of Indianapolis.
Michiana Health Information Network has added Elkhart General Healthcare System to its health information
exchange service. Doctors in Elkhart can now receive electronic copies of medical records and laboratory results from Elkhart
General Hospital quickly and without the privacy issues of e-mail. Once fully implemented, all Elkhart physicians with electronic
health records will have the ability to instantly receive hospital reports, laboratory results and radiology reports directly
into their EHR systems. Michiana Health Information Network, established in 1999, includes more than 3,200 community health
care professionals in northern Indiana and southwest Michigan.
In its latest response to withering criticism of its breast-cancer policies, WellPoint Inc. started Tuesday
to pay for all breast cancer patients to stay two days in a hospital after mastectomy surgery. Some states already require
insurers to cover hospital stays of 48 hours if the patient and her doctor wanted that much time for recovery after mastectomy
surgery. But Indiana requires payment only for a 24-hour stay. Now, WellPoint will make the 48-hour policy standard for its
customers in any state. Indianapolis-based WellPoint has been under fire since a Reuters article in April said the company
uses a computer algorithm to target breast cancer patients for cancellation of their policies. WellPoint has repeatedly called
the article’s claims “inaccurate and grossly misleading.” But the article provided the basis for sharp criticism
of WellPoint from President Obama, Health and Human Services Secretary Kathleen Sebelius and dozens of members of Congress.