2025 Innovation Issue: What’s a startup? Most say it’s a company that’s young, disruptive and scalable
Even seasoned entrepreneurs and business executives have different takes about exactly what constitutes a startup—or at least a successful one.
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Startups to watch: Adipo Therapeutics LLC
Adipo is developing a new approach to obesity treatment that converts subcutaneous white fat into healthier, energy-burning brown fat.
Startups to watch: Primary Record
Founders: Jean Ross, Jim McIntosh Established: 2020 Top executives: Jean Ross, CEO Jim McIntosh, head of product Dr. Chris Ross, chief medical officer Equity raised: $1 million pre-seed round that closed in December 2023 2024 revenue: less than $20,000 Projected 2025 revenue: more than $250,000 Employees: 3 Location: Fishers Affiliations: none Patents: none What does […]
Startups to watch: ReproHealth Technologies
ReproHealth makes devices to improve assisted reproduction in animals, including through in vitro fertilization and artificial insemination.
Startups to watch: Grannus Therapeutics
Founders: John Foglesong, Sanket Mishra, Brian Blagg Established: 2021 Top executives: John Foglesong, CEO and president Daniel Flynn, chief strategy officer Michael Rafferty, head of preclinical development Sanket Mishra, vice president of research Equity raised: $1 million seed round, $800,000 and $1 million from two bridge rounds, $700,000 Small Business Technology Transfer grant (non-equity) from […]
2025 Innovation Issue: Startup expert says founders need business skills in addition to a great idea
Rob Mathews, executive director of Ball State University’s Entrepreneurship Center, views leadership and innovation as inseparable attributes for a startup.
Innovation Issue 2025
Meet Indiana companies seeking to disrupt the health care, defense, agriculture, wearable device and even death industries using AI, quantum computing and other emerging technologies. These 20 companies are seeking to disrupt their industries Is the next Uber, SpaceX or Airbnb percolating right now in an Indiana co-working space, a university lab or even on […]
Indiana Historical Society to keep its building, land after agreement with governor’s office
The deal follows concerns raised during the 2025 legislative session over proposed budget language that could have stripped the nonprofit of its biggest asset.
Hoosier business executives say to voice tariff concerns, find alternative trade pathways
Representatives from Eli Lilly, Cook Medical and other Hoosier businesses gave advice about tariffs during the Indiana District Export Council’s annual trade and business conference Thursday at Newfields.
‘Innovation at every stage’: Lilly to invest up to $250M in broadened alliance with Purdue University
The extended partnership holds the potential to be the largest industry-academic agreement of its kind in the United States, Purdue President Mung Chiang said.
Residents, attorneys raise questions about city’s land acquisitions in planned Monon Trail expansion
City officials say the acquisition process is intended to clear up the ownership of the former rail line as they expand the trail from 10th to 96th streets.
U.S. Sen. Todd Young partners on bipartisan bill to jumpstart domestic shipbuilding industry
Young, R-Indiana, and fellow Sen. Mark Kelly, D-Arizona, reintroduced legislation to jumpstart the country’s “rusted” shipbuilding industry and increase onshore ship production that has largely shifted to China.
Rally innovation conference to continue as planned, likely without state support
Rally innovation conference creator Elevate Ventures says Rally will take place as planned this year, but organizers are not counting on financial support from the Indiana Economic Development Corp.
Indiana crackdown on ‘predatory’ towing to take effect in July
Surveyed commercial carriers logged the most “predatory” towing incidents relative to mileage in Indiana between 2021 and 2023, according to a report by the American Transportation Research Institute.
Trump floats cutting China tariffs to 80% ahead of trade meeting
Top U.S. officials are set to meet with a high-level Chinese delegation in Switzerland in the first major talks between the two nations since Trump sparked a trade war with stiff tariffs on imports.
Tech industry warns investment pledges hinge on research tax break
Major tech companies lobbying to salvage a tax deduction for research and development say they might pull back from high-profile pledges of new U.S. investments if Congress doesn’t fully reinstate the break.
Brad Rateike: I unloaded the dishwasher without being prompted
After having a long-term roommate for nearly 11 years, it might be time to take McRaven’s advice and step it up around the house.
Deborah Daniels: Are the Oscars an example of DEI gone too far? Maybe.
Might the vast overreaction on the right not have occurred but for the dogmatic insistence on DEI quotas on the left?
Claire Fiddian-Green: A proposed new approach for career advising in Indiana
The world of work evolves continuously, and the pace has only increased due to the impact of automation and AI.
Abdul-Hakim Shabazz: The older I get, the more ‘liberal’ I get.
When I say I’m more free market, that means I am anti-tariff.