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Articles

Brain barrier breached in push to deliver Alzheimer’s drug

May 25, 2011

Scientists with Roche Holding AG, the parent company of Indianapolis-based Roche Diagnostics Corp., may have found a way to overcome a blood barrier that keeps drugs from directly entering the brain, potentially opening new pathways to attack Alzheimer’s disease.

Family has steely plan for shifting business to next generation

May 25, 2011

Westfield Steel owners Karyn and Fred Prine are well on the way to transitioning to the next generation—son Fritz—thanks to timely planning.

MARCUS: Numbers say Indiana’s economy isn’t healthy

May 26, 2011

Usually, when an unemployed person gets a job, the number of people unemployed goes down and the number employed goes up. That’s a healthy economy.

CEOs see stock windfall after market crash

May 26, 2011

Executives at Indiana’s public companies got rich in the down-and-up market, even when investors didn't. CNO Financial's Jim Prieur, for example, received stock grants now worth $4.4M, despite share prices that are 40 percent lower than three years ago. With searchable database.

Total pay for executives surged in 2010

May 26, 2011

Total executive compensation at Indiana’s largest public companies continued to rise sharply coming out of the recession, even though many of them have yet to erase the red ink in their shareholders’ portfolios.

Life sciences logistics firm opens new tissue storage facility

May 27, 2011

BioStorage Technologies’ $4.6 million facility, located near the Indianapolis International Airport, will be used to prepare, store and transport tissue and blood samples.

Company news

May 30, 2011

Eli Lilly and Co. lost the first round of its family legal dispute with Amylin Pharmaceuticals Inc. The California-based company won an injunction that prevents Indianapolis-based Lilly from using the same sales force to sell the Amylin-created drug Byetta as well as a new drug called Tradjenta, made by Germany-based Boerhinger Ingelheim GmbH. Both drugs are for patients with Type 2 diabetes, and therefore would compete against each other. Byetta is an injectable medicine and Tradjenta is an oral agent. Lilly said it is disappointed with the first ruling and will keep fighting Amylin’s lawsuit.

Franklin-based Johnson Memorial Hospital and Indianapolis-based Community Health Network will put their clinical collaboration agreement into effect June 1. The agreement was reached in February, after Johnson Memorial also considered proposals from Franciscan St. Francis and Indiana University Health. The deal, while not an acquisition, solidifies Community’s presence in the fast-growing southern suburbs of Indianapolis, where it already maintains a 150-bed hospital along County Line Road. Johnson Memorial, located nearly 15 miles south, is licensed for 101 beds. Hospitals and doctors are being pushed by health insurance plans to partner up to keep patients healthy—both before and after they actually seek medical care. But Community and Johnson Memorial are also looking to expand their  offerings, particularly for heart patients.

Advion BioServices, a subsidiary of New York-based Advion BioSciences Inc., has opened its 22,000-square-foot drug-discovery and bioanalytical laboratory at the Purdue Research Park of Indianapolis' technology center at the Ameriplex Business Park near the Indianapolis International Airport. The new facility, staffed with 50 employees, was announced in March. Advion, a contract-research organization, will focus on earlier-stage, drug-discovery and metabolism bioanalytical services that evaluate how a potential new medicine is absorbed and metabolized in experimental models. Many of these services generate the data needed to prepare a molecule for human trials.

Indianapolis-based BioStorage Technologies announced Thursday it has opened a 60,000-square-foot biorepository facility in Indianapolis. The $4.6 million facility, located near the Indianapolis International Airport, will be used to prepare, store and transport tissue and blood samples. BioStorage serves biotech companies, such as Massachusetts-based Biogen Idec, as well as medical-device makers such as Minnesota-based Medtronic Inc. and academic research institutions. The facility will allow BioStorage to prepare samples for its clients via automated equipment, which the company says provides the accuracy needed by high-volume medical researchers. BioStorage, founded in 2002, is one of a handful of central Indiana companies that have developed a specialty in life sciences logistics. Others include Indianapolis-based Sentry BioPharma Services Inc., Plainfield-based MD Logistics Inc., and Bloomington-based BioConvergence LLC.

Decision unclear on Purdue president’s future

May 31, 2011

Purdue University leaders aren't saying whether President France Cordova will stay on the job after she reaches its normal retirement age next year.

Electric vehicles gain traction in region

June 1, 2011

Indianapolis has one of the highest concentrations of plug-in electric vehicle drivers in the nation, an industry official says.

MARCUS: Should we have commuting policies?

June 2, 2011

In 2009, 80 percent of Hoosiers worked in the county where they lived, with the other 20 percent going elsewhere to work. Hardly a change from data 10 years earlier.

KENNEDY: We need to get our civics game on

June 2, 2011

Right now, Americans are deeply involved in one of our periodic debates about government spending and the budget deficit. Important as that is, I am more concerned about our civic deficit—the widespread lack of basic constitutional literacy.

Startup aims to make online car shopping easier

June 2, 2011

The horrible experience John Kohlmeyer’s mother had trying to shop for a car online inspired him to create DriveVelocity, a company that not only overhauls dealer websites but also packages all their Web-based customer-relationship tools.

Indiana edges toward education guarantees

June 8, 2011

The state is moving to adopt a system that ensures more high school graduates can perform in college or on the job.

GUILLAUME: Front-load investment in the next generation of workers

June 8, 2011

Rate of return on early childhood education is much greater than spending in later years of school, research shows.

DWYER: Hiring costs can be sliced when industry cooperates

June 8, 2011

Manufacturers and distributors often avoid existing training programs.

WOUDENBERG: Indiana Supremes blew it with police case

June 8, 2011

Rather than limit the decision to its facts, the court instead sweepingly discarded the reasonable resistance right in its entirety.

VAUGHN: State protects insurers better than consumers

June 8, 2011

Instead of an effective regulatory environment, the facts suggest [Insurance Commissioner Stephen] Robertson’s rubber stamp for rate increases is getting a real workout.

KETZENBERGER: Americans prefer shiny objects to substance

June 8, 2011

Gov. Mitch Daniels’ marital history has no bearing on his ability to steer the country and reveals no damning character flaws.

Few local charities growing their influence outside Indiana

June 8, 2011

At a time when the not-for-profit sector is buzzing with terms like “scaling impact” and “venture philanthropy,” few native not-for-profits have sown seeds outside Indiana. Leaders and funders emphasize the need the serve the local market first.

ANNALA: Sweeping cultural change has bettered not-for-profits

June 8, 2011

Times have changed, and along with those changes during the past four-plus decades have come at least four aha’s! for Ellen Annala, longtime CEO of the United Way of Central Indiana.

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